Regression coefficients of the presence and number of disabilities for the risk of mortality in elderly men
| Variable | Model 1 HR (95% CI) | p Value | Model 2 HR (95% CI) | p Value | Model 3 HR (95% CI) | p Value | Model 4 HR (95% CI) | p Value | Model 5 HR (95% CI) | p Value |
|---|---|---|---|---|---|---|---|---|---|---|
| Presence of disability | 3.47 (1.78 to 6.77) | <0.001 | 2.43 (1.21 to 4.88) | 0.012 | 2.31 (1.11 to 4.80) | 0.026 | 2.00 (0.95 to 4.21) | 0.069 | 1.61 (0.69 to 3.73) | 0.268 |
| Number of disabilities | ||||||||||
| 0 | 1.0 (ref) | 1.0 (ref) | 1.0 (ref) | 1.0 (ref) | 1.0 (ref) | |||||
| 1 | 1.01 (0.35 to 2.89) | 0.984 | 0.92 (0.32 to 2.64) | 0.875 | 0.95 (0.33 to 2.75) | 0.927 | 0.82 (0.28 to 2.43) | 0.716 | 0.73 (0.25 to 2.19) | 0.578 |
| 2 | 2.67 (1.10 to 6.49) | 0.030 | 1.82 (0.73 to 4.53) | 0.196 | 1.55 (0.57 to 4.20) | 0.387 | 1.48 (0.55 to 4.02) | 0.441 | 1.12 (0.36 to 3.48) | 0.844 |
| 3 | 3.55 (1.08 to 11.72) | 0.037 | 2.46 (0.73 to 8.28) | 0.146 | 2.51 (0.74 to 8.57) | 0.142 | 2.12 (0.617 to 7.30) | 0.233 | 1.65 (0.46 to 5.87) | 0.439 |
| 4 | 15.16 (4.45 to 51.67) | <0.001 | 10.04 (2.80 to 36.00) | <0.001 | 10.63 (2.82 to 40.14) | <0.001 | 6.30 (1.16 to 34.14) | 0.033 | 5.62 (0.97 to 32.32) | 0.053 |
| 5 | 4.50 (0.62 to 32.74) | 0.979 | 3.63 (0.46 to 28.44) | 0.981 | 3.75 (0.47 to 29.92) | 0.981 | 4.14 (0.50 to 34.64) | 0.981 | 4.50 (0.51 to 39.75) | 0.981 |
| ptrend | <0.001 | 0.013 | 0.017 | 0.265 | 0.381 | |||||
| Components of disability | ||||||||||
| ADL | 2.15 (0.67 to 6.95) | 0.199 | 2.10 (0.65 to 6.83) | 0.218 | 2.21 (0.66 to 7.36) | 0.196 | 1.31 (0.35 to 4.82) | 0.690 | 0.97 (0.24 to 3.83) | 0.961 |
| IADL | 5.18 (2.56 to 10.51) | <0.001 | 4.77 (2.26 to 10.06) | <0.001 | 5.27 (2.42 to 11.50) | <0.001 | 3.20 (1.14 to 9.00) | 0.028 | 2.12 (0.70 to 6.47) | 0.185 |
| LSA | 3.10 (1.23 to 7.84) | 0.017 | 2.69 (1.03 to 7.00) | 0.043 | 2.78 (1.06 to 7.30) | 0.038 | 1.74 (0.62 to 4.89) | 0.295 | 1.28 (0.44 to 3.79) | 0.652 |
| LEM | 3.76 (1.93 to 7.35) | <0.001 | 2.82 (1.42 to 5.61) | 0.003 | 2.82 (1.35 to 5.88) | 0.006 | 2.80 (1.32 to 5.92) | 0.007 | 2.30 (1.04 to 5.12) | 0.041 |
| GPA | 2.22 (1.25 to 3.99) | 0.007 | 1.95 (1.08 to 3.51) | 0.026 | 1.86 (1.01 to 3.42) | 0.047 | 1.53 (0.81 to 2.90) | 0.194 | 1.17 (0.58 to 2.34) | 0.662 |
Model 1=unadjusted.
Model 2=model 1+(age, gender, race/ethnicity, marital status).
Model 3=model 2+(serum LDL, serum CRP, serum total bilirubin, serum glucose).
Model 4=model 3+(hypertension, diabetes mellitus, stroke, heart disease, CAD).
Model 5=model 4+(serum albumin, cognitive impairment, number of prescription medications taken).
ADL, activities of daily living; CAD, coronary artery disease; CRP, C-reactive protein; GPA, general physical activities; IADL, instrumental activities of daily living; LDL, low-density lipoprotein; LEM, lower extremity mobility; LSA, leisure and social activities.