Variable | Model 1 HR (95% CI) | p Value | Model 2 HR (95% CI) | p Value | Model 3 HR (95% CI) | p Value | Model 4 HR (95% CI) | p Value | Model 5 HR (95% CI) | p Value |
---|---|---|---|---|---|---|---|---|---|---|
Presence of disability | 3.05 (1.47 to 6.31) | 0.003 | 2.87 (1.38 to 5.95) | 0.005 | 2.75 (1.31 to 5.80) | 0.008 | 2.95 (1.37 to 6.38) | 0.006 | 2.69 (1.22 to 5.96) | 0.014 |
Number of disabilities | ||||||||||
0 | 1.0 (ref) | 1.0 (ref) | 1.0 (ref) | 1.0 (ref) | 1.0 (ref) | |||||
1 | 1.56 (0.61 to 3.97) | 0.351 | 1.43 (0.56 to 3.67) | 0.457 | 1.44 (0.56 to 3.74) | 0.449 | 1.43 (0.54 to 3.78) | 0.472 | 1.51 (0.55 to 4.11) | 0.424 |
2 | 2.71 (1.06 to 6.91) | 0.037 | 2.60 (1.01 to 6.67) | 0.047 | 2.41 (0.93 to 6.24) | 0.071 | 2.48 (0.93 to 6.60) | 0.070 | 2.20 (0.79 to 6.07) | 0.130 |
3 | 3.27 (0.75 to 14.35) | 0.116 | 3.16 (0.72 to 13.97) | 0.129 | 3.30 (0.73 to 14.88) | 0.120 | 3.65 (0.77 to 17.29) | 0.103 | 3.12 (0.64 to 15.57) | 0.166 |
4 | 5.46 (1.25 to 23.98) | 0.024 | 3.98 (0.89 to 17.81) | 0.071 | 4.31 (0.94 to 19.85) | 0.061 | 4.78 (1.01 to 22.61) | 0.049 | 4.22 (0.78 to 22.87) | 0.095 |
5 | 18.05 (2.36 to 138.12) | 0.005 | 14.98 (1.78 to 125.96) | 0.013 | 23.81 (1.97 to 288.03) | 0.013 | 76.29 (2.54 to 2293.08) | 0.013 | 202.16 (5.14 to 7946.10) | 0.005 |
ptrend | 0.012 | 0.036 | 0.048 | 0.036 | 0.031 | |||||
Components of disability | ||||||||||
ADL | 4.81 (1.68 to 13.74) | 0.003 | 4.20 (1.46 to 12.07) | 0.008 | 4.34 (1.43 to 13.13) | 0.009 | 4.12 (1.24 to 13.67) | 0.021 | 4.44 (1.31 to 15.01) | 0.017 |
IADL | 1.39 (0.42 to 4.55) | 0.590 | 1.11 (0.34 to 3.67) | 0.863 | 1.13 (0.33 to 3.85) | 0.840 | 1.12 (0.32 to 3.91) | 0.859 | 0.99 (0.27 to 3.63) | 0.989 |
LSA | 4.03 (1.41 to 11.50) | 0.009 | 3.01 (1.04 to 8.71) | 0.043 | 3.15 (1.04 to 9.52) | 0.042 | 3.18 (1.03 to 9.85) | 0.045 | 3.15 (0.94 to 10.56) | 0.063 |
LEM | 2.83 (1.37 to 5.85) | 0.005 | 2.81 (1.35 to 5.84) | 0.006 | 2.73 (1.31 to 5.69) | 0.007 | 2.96 (1.39 to 6.28) | 0.005 | 2.68 (1.24 to 5.80) | 0.012 |
GPA | 1.92 (0.97 to 3.80) | 0.060 | 1.72 (0.86 to 3.44) | 0.122 | 1.70 (0.85 to 3.40) | 0.137 | 1.75 (0.86 to 3.58) | 0.123 | 1.74 (0.83 to 3.62) | 0.141 |
Model 1=unadjusted.
Model 2=model 1+(age, gender, race/ethnicity, marital status).
Model 3=model 2+(serum LDL, serum CRP, serum total bilirubin, serum glucose).
Model 4=model 3+(hypertension, diabetes mellitus, stroke, heart disease, CAD).
Model 5=model 4+(serum albumin, cognitive impairment, number of prescription medications taken).
ADL, activities of daily living; CAD, coronary artery disease; CRP, C-reactive protein; GPA, general physical activities; IADL, instrumental activities of daily living; LDL, low-density lipoprotein; LEM, lower extremity mobility; LSA, leisure and social activities.