Table 2

p Values for each interaction between the continuous baseline predictor and PEEP intervention for each outcome in the three included trials

Trial/predictor60 days mortalityTime to deathTime to unassisted breathing
LOVS
 BMI0.73310.35370.7507
 Estimated RC0.10780.09570.3264
 PaO2/FiO20.12470.02960.0325
 Oxygenation index0.43370.12590.2594
EXPRESS
 BMI0.69890.70910.7294
 Estimated RC0.69220.70530.4629
 PaO2/FiO20.55110.60950.7587
 Oxygenation index0.32870.30410.9492
ALVEOLI
 BMI0.18440.08940.8589
 Estimated RC0.54380.79380.1192
 PaO2/FiO20.97850.76470.2002
 Oxygenation index0.79080.88350.8046
  • BMI, body mass index; FiO2, fraction of inspired oxygen; PaO2, arterial partial oxygen pressure (mm Hg); PEEP, positive end-expiratory pressure; RC, respiratory compliance (tidal volume in mL/inspiratory plateau pressure−PEEP in mm Hg).