n (%) | |
---|---|
Age at index diagnosis date* | |
18–29 | 948 (6) |
30–39 | 1452 (9) |
40–49 | 2164 (13) |
50–59 | 2736 (17) |
60–69 | 2937 (18) |
70–79 | 3127 (20) |
80+ | 2676 (17) |
Median (25–75%) | 62 (47–75) |
Gender | |
Male | 8406 (52) |
Female | 7634 (48) |
Date of index diagnosis | |
2000–2002 | 3336 (21) |
2003–2005 | 3867 (24) |
2006–2008 | 3962 (25) |
2009–2012 | 4875 (30) |
Index diagnosis | |
Jaundice† | 6951 (43) |
Obstructive jaundice | 2531 (16) |
Cholangitis | 1144 (7) |
Hepatitis unspecified | 408 (4) |
Chronic hepatitis | 541 (3) |
Other liver disorders | 528 (3) |
Biopsy of liver | 412 (3) |
Any other code‡ | 3223 (20) |
Liver test results§ | |
No liver test result | 7354 (46) |
Test results before index diagnosis | 4039 (25) |
Test results on or after index diagnosis | 4647 (29) |
HES record¶ | |
No HES record | 3392 (21) |
HES record before index diagnosis | 923 (6) |
HES record on or after index diagnosis | 11 725 (73) |
ONS mortality record** | |
No ONS mortality record | 10 157 (63) |
Had ONS mortality record | 5883 (37) |
*Date of diagnosis with one of the potential cholestatic liver injury codes listed in the online supplementary material.
†Includes codes ‘Jaundice—symptom’, ‘[d]jaundice’, ‘O/e—jaundiced’, ‘[d]jaundice (not of newborn)’.
‡People in this group had an index diagnosis of any of the other codes listed in the online supplementary material.
§No liver test results=none within 90 days either side of index diagnosis date; test results before/after=closest liver test result was before/after the index and within 90 days.
¶No HES record=no HES record ever (n=1080) or no record within 365 days either side of index diagnosis date (n=2312); HES record before/after index diagnosis=closest HES record was before/after the index and within 365 days.
**ONS mortality record at any time (after index diagnosis).
CPRD, Clinical Practice Research Datalink; HES, Hospital Episodes Statistics; ONS, Office of National Statistics.