Median and mean durations of infection in months and proportion of persistent infection for individual and grouped HPV types (combined cervical and cervicovaginal samples)
| Liberal definition: clearance defined as first negative results postinfection | Conservative definition: clearance defined as two consecutive negative results postinfection | |||||||
|---|---|---|---|---|---|---|---|---|
| HPV type, species | No. of events | Median duration of infection (95% CI) | Mean duration of infection (95% CI) | % of persistent infection (1-year) | No. of events | Median duration of infection (95% CI) | Mean duration of infection (95% CI) | % of persistent infection (1-year) |
| HPV6 | 43 | 6.5 (5.7 to 9.0) | 9.5 (7.5 to 11.5) | 16.1 | 41 | 7.2 (5.7 to 9.6) | 10.0 (7.9 to 12.2) | 18.2 |
| HPV11 | 24 | 7.2 (5.8 to 11.7) | 9.2 (6.9 to 11.4) | 25.5 | 23 | 9.8 (6.0 to 12.6) | 11.0 (7.9 to 14.1) | 32.3 |
| HPV16 | 82 | 11.8 (10.3 to 16.7) | 15.8 (13.0 to 18.5) | 49.0 | 69 | 16.9 (11.7 to 22.6) | 21.3 (17.3 to 25.2) | 60.6 |
| HPV18 | 61 | 6.2 (5.8 to 11.1) | 10.8 (8.3 to 13.3) | 33.0 | 57 | 7.7 (5.9 to 12.2) | 12.1 (9.4 to 14.9) | 39.3 |
| HPV31 | 44 | 7.4 (5.9 to 12.1) | 10.9 (8.4 to 13.4) | 36.6 | 39 | 10.6 (6.7 to 16.7) | 14.0 (10.8 to 17.1) | 46.7 |
| HPV33 | 27 | 8.0 (6.2 to 10.6) | 10.0 (7.3 to 12.7) | 27.1 | 24 | 8.7 (6.2 to 13.3) | 11.3 (8.3 to 14.3) | 40.2 |
| HPV34 | 8 | 6.0 (2.5 to 11.5) | 8.0 (5.1 to 10.8) | 12.5 | 8 | 6.0 (2.5 to 11.5) | 8.0 (5.1 to 10.8) | 12.5 |
| HPV35 | 21 | 12.1 (6.2 to 16.6) | 14.8 (10.7 to 18.8) | 50.3 | 16 | 14.3 (11.3 to 24.6) | 17.6 (12.7 to 22.5) | 59.0 |
| HPV39 | 49 | 6.5 (6.0 to 8.3) | 11.0 (8.5 to 13.5) | 30.2 | 44 | 8.1 (6.5 to 14.1) | 13.8 (10.7 to 16.9) | 40.4 |
| HPV40 | 23 | 6.0 (4.4 to 8.1) | 7.2 (5.5 to 8.9) | 13.5 | 21 | 6.0 (4.4 to 9.5) | 7.7 (5.8 to 9.7) | 17.4 |
| HPV42 | 11 | 6.0 (3.2 to 10.0) | 6.8 (5.2 to 8.3) | 0.0 | 9 | 7.2 (3.2 to 34.8) | 13.0 (5.2 to 20.8) | 22.9 |
| HPV43 | 20 | 5.9 (4.4 to 8.5) | 7.9 (5.5 to 10.4) | 17.1 | 15 | 6.0 (4.4 to 16.6) | 10.0 (6.8 to 13.2) | 31.0 |
| HPV44 | 21 | 6.9 (4.4 to 13.9) | 11.2 (7.0 to 15.4) | 32.6 | 18 | 7.0 (6.0 to 19.3) | 14.4 (9.1 to 19.8) | 39.4 |
| HPV45 | 28 | 7.0 (5.5 to 9.2) | 8.9 (6.8 to 11.0) | 21.8 | 25 | 7.2 (5.6 to 11.6) | 9.8 (7.3 to 12.2) | 24.9 |
| HPV51 | 82 | 7.4 (6.0 to 10.6) | 11.3 (9.1 to 13.5) | 33.6 | 69 | 10.3 (6.9 to 12.5) | 15.4 (11.7 to 19.1) | 40.8 |
| HPV52 | 76 | 10.7 (7.2 to 14.5) | 14.9 (12.3 to 17.5) | 45.3 | 64 | 16.8 (10.8 to 21.4) | 19.9 (16.2 to 23.6) | 60.3 |
| HPV53 | 81 | 11.2 (9.3 to 12.0) | 12.0 (10.3 to 13.6) | 40.8 | 70 | 12.1 (11.1 to 14.7) | 15.5 (12.9 to 18.0) | 50.1 |
| HPV54 | 38 | 6.0 (5.3 to 7.6) | 8.6 (6.8 to 10.4) | 29.5 | 32 | 6.9 (5.8 to 12.5) | 10.2 (8.0 to 12.4) | 39.4 |
| HPV56 | 46 | 6.1 (5.3 to 12.1) | 11.9 (8.8 to 15.0) | 36.5 | 39 | 12.1 (6.0 to 18.3) | 14.7 (11.0 to 18.5) | 52.9 |
| HPV58 | 26 | 9.7 (5.3 to 12.0) | 11.5 (8.4 to 14.6) | 30.8 | 24 | 11.4 (7.5 to 21.8) | 13.7 (10.4 to 17.0) | 44.8 |
| HPV59 | 25 | 7.0 (5.3 to 11.6) | 8.5 (6.5 to 10.5) | 28.1 | 22 | 7.3 (5.3 to 13.4) | 9.0 (6.8 to 11.2) | 34.4 |
| HPV66 | 59 | 6.5 (5.8 to 9.3) | 9.4 (7.7 to 11.0) | 25.4 | 50 | 9.0 (6.0 to 11.6) | 12.4 (9.6 to 15.2) | 36.7 |
| HPV68 | 45 | 6.2 (5.8 to 12.3) | 10.7 (8.4 to 13.1) | 36.6 | 42 | 7.8 (6.0 to 14.0) | 12.7 (10.1 to 15.3) | 45.1 |
| HPV70 | 18 | 10.2 (5.5 to 18.9) | 18.0 (9.9 to 26.0) | 42.5 | 14 | 12.5 (6.0 to 25.8) | 22.5 (12.8 to 32.2) | 53.1 |
| HPV74 | 24 | 6.5 (5.3 to 18.7) | 12.2 (8.8 to 15.6) | 42.0 | 22 | 11.0 (5.3 to 18.7) | 14.1 (9.9 to 18.3) | 48.6 |
| Any HPV | 251 | 14.5 (11.8 to 16.8) | 21.9 (19.4 to 24.3) | 53.7 | 210 | 25.0 (18.0 to 27.9) | 29.7 (26.7 to 32.7) | 66.4 |
| HR-HPV | 232 | 13.7 (10.6 to 16.8) | 19.5 (17.3 to 21.8) | 54.1 | 187 | 24.6 (20.1 to 28.8) | 28.1 (25.0 to 31.2) | 67.4 |
| LR-HPV | 150 | 8.6 (6.5 to 10.9) | 11.6 (10.1 to 13.1) | 32.3 | 130 | 11.6 (10.2 to 12.5) | 14.8 (12.8 to 16.8) | 44.3 |
| Species-6 | 146 | 9.9 (7.5 to 11.6) | 12.1 (10.6 to 13.7) | 39.3 | 122 | 11.7 (9.7 to 13.0) | 16.5 (14.0 to 19.0) | 48.9 |
| Species-7 | 148 | 7.3 (6.2 to 11.3) | 12.6 (10.7 to 14.4) | 38.9 | 133 | 11.7 (7.3 to 14.1) | 16.4 (14.0 to 18.7) | 49.4 |
| Species-8 | 40 | 5.9 (5.0 to 6.2) | 7.4 (5.8 to 9.0) | 15.0. | 32 | 6.0 (5.5. to 9.5) | 8.8 (6.7 to 11.0) | 24.1 |
| Species-9 | 167 | 13.1 (10.6 to 16.7) | 16.7 (14.7 to 18.8) | 52.1 | 136 | 20.0 (15.9 to 23.3) | 23.9 (20.7 to 27.1) | 65.1 |
| Species-10 | 79 | 7.0 (6.0 to 8.8) | 10.0 (8.3 to 11.7) | 29.0 | 72 | 8.7 (6.2 to 11.7) | 11.9 (9.8 to 14.0) | 35.8 |
α species 6=HPVs 53, 56, 66; α species 7=HPVs 18, 39, 45, 59, 68, 70; α species 8=HPVs 40, 43; α species 9=HPVs 16, 31, 33, 35, 52, 58; α species 10=HPVs 6, 11, 44.
HPV, human papillomavirus; HR-HPV, high-risk HPV (16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66 and 68); LR-HPV, low-risk HPV (6, 11, 34, 40, 42, 43, 44, 53, 54, 59, 70 and 74).