TableĀ 2

Data extraction elements

Systematic review questionData extraction
What are the current treatment options (medicinal and otherwise) in use?
  • Study aim and type

  • Treatment option (description/dosage)

  • Prescription only/parent purchase/fees

  • Timescales/length of treatment

  • Number of treatments

  • Management of adverse effects

  • Management of comorbidities

What are the direct and indirect costs for parents?
  • Study aim and type

  • Burden components (eg, over the counter treatments, changes in infant formula purchases and the loss of income through time taken off work/inability to return to work due to caring for the infant or attend clinical appointments)

  • Dates of data collection

  • Currency

  • The value of any costs identified

What are the current estimates of the COI of FGIDs and related signs and symptoms?
  • Study aim and type

  • Definition of COI

  • Burden components (eg, prescribed treatments, visits to health professionals)

  • Dates of data collection

  • Currency

  • Methods of data identification/collection

  • Results: COI

  • Limitations