Published and unpublished studies focusing on assessment of p53 as a potential prognostic factor in bladder cancer
| Reference (I) or contact person and year of analysis (II) | Reporting period* | Study size (number of events) | Tumour stage Tumour grade | Surgical treatment |
|---|---|---|---|---|
| (I) Published studies | ||||
| Place of reporting institution: Düsseldorf (Germany) | ||||
| Jankevicius et al (2002)45 | NR | 60 (NR)† A: 39 (NR) B: 21 (NR) | T1–T4 NR | TUR in 39 patients, cystectomy in 21 patients |
| Schmitz-Dräger et al (1997)38 | NR | 61 (28) | Ta–T4 G1–G3 | NR |
| Schmitz-Dräger et al (1994)33‡ | 1985–1993 | 43 (7) | Ta–T4 G1–G3 | NR |
| Place of reporting institution: Erlangen-Nürnberg and Halle (Germany) | ||||
| Rödel et al (2000)41 | 1982–1996 | 70 (NR,NR)¶ | T1–T4 G1–G4 | TUR |
| Place of reporting institution: Hamburg (Germany) | ||||
| Friedrich et al (1997)37 | NR | 53 (20) | Ta–T1 G1–G3 | TUR |
| Friedrich et al (2001)42‡ | NR | 40 (14) | Ta, T1 G1–G3 | TUR |
| Place of reporting institution: Hannover (Germany) | ||||
| Serth et al (1995)36 | NR | 69 (13) | T1 NR | TUR |
| Bokemeyer et al (1994)31‡ | NR | 41 (8) | T1 NR | TUR |
| Kuczyk et al (1994)32‡ | NR | 41 (8) | T1 G1–G2 | TUR |
| Kuczyk et al (1995)§35‡ | NR | 41 (8) | T1 G1–G2 | TUR |
| Kuczyk et al (1995)34 | NR | 44 (23) | T2–T4 G2–G3 | cystectomy |
| Place of reporting institution: Cologne (Germany) | ||||
| Hake et al (1993)§30 | NR | 119 (61)† A: 40 (21) B: 79 (40) | Ta, T1–T2 G1–G2 | NR |
| Vorreuther et al (1997)40‡ | 1978–1988 | 104 (53)** A: 59 (29) B: 45 (24) C: 40 (22) D: 64 (31) | Ta, T1 G1–G2 | TUR |
| Place of reporting institution: Lübeck (Germany) | ||||
| Krüger et al (2005)47 | 1988–1998 | 73 (52,27)¶ | T1 G2–G3 | TUR |
| Krüger et al (2003)46‡ | 1987–1997 | 54 (43,19)¶ | T1 G2–G3 | TUR |
| Mahnken et al (2005)48‡ | 1987–1999 | 69 (48,27)¶ | T1 G2–G3 | TUR |
| Place of reporting institution: Mainz (Germany) | ||||
| Leissner et al (2001)43 | 1990–1997 | 70 (34,14)¶ | Ta G2 | TUR |
| Place of reporting institution: Mainz and Magdeburg (Germany) | ||||
| Wolf et al (2001)44 | 1989–1998 | 30 (11) | T1–T4 G3 | TUR in 5 patients, cystectomy in 25 patients |
| Place of reporting institution: Münster (Germany) | ||||
| van Ahlen et al (1997)§39 | 1988–1992 | 100 (NR,63)¶ | Ta–T4 G1–G4 | cystectomy |
| (II) Unpublished studies | ||||
| Place of reporting institution: Aachen (Germany) | ||||
| US#1: Lehnert TG (1998) | NR | 121 (NR) | Ta–T4 G1–G3 | NR |
| Place of reporting institution: Erlangen (Germany) | ||||
| US#2: Perez R (2001) | NR | 107 (NR) | Ta, T1–T2 G1–G3 | NR |
| Place of reporting institution: Heidelberg (Germany) | ||||
| US#3: Kunkel A (1996) | NR | 33 (NR) | T1 G1–G3 | NR |
| Place of reporting institution: Mainz (Germany) | ||||
| US#4: Adler J (1998) | NR | 49 (NR) | Ta–T4 G1–G4 | NR |
| Place of reporting institution: Saarbrücken/Homburg (Germany) | ||||
| US#5: Gerber M (2003) | NR | 115 (NR) | T1–T4 G2–G4 | NR |
*Reporting period usually refers to the time period of patient inclusion.
†Analysis was only done within two non-overlapping subgroups.
‡Associated (excluded) studies with the respective included study mentioned in row above.
¶Studies assessing two end points.
§Publication in German language.
**Analysis was only done within partly overlapping subgroups (A and B as well as C and D add up to whole study population).
NR not reported; TUR, transurethral resection.