Estimates of biological interaction between anxiety and depression symptoms and their effects on glycaemic control in participants with T2DM
| Measures of biological interaction | Estimate (95% CI) |
|---|---|
| RERI | 4.93 (2.09 to 7.87) |
| AP | 0.27 (0.12 to 0.45) |
| S | 1.41 (1.22 to 1.66) |
Reference group: anxiety symptom score <50 and depressive symptom score <50. Models were adjusted for age, sex, education level, marital status, exercise, income, BMI, disease duration, comorbidity, complications, smoking, drinking, insulin use and poor sleep quality.
AP, attributable proportion due to interaction; BMI, body mass index; RERI, relative excess risk due to interaction; S, synergy index; T2DM, type 2 diabetes mellitus.