Table 3

Multiple linear regression analysis of predictors of serum B12, folate and homocysteine

VariablesSerum B12*Serum folateHomocysteine*
β coefficientp Valueβ coefficientp Valueβ coefficientp Value
AgeNSNS0.180.001
BMINSNSNS
Smoking–0.12<0.05NSNS
AlcoholNSNSNS
Oral contraceptive use−0.29<0.0010.11<0.05NS
TC:HDL ratio*NSNSNS
Vegetarian or vegan diet−0.18<0.01NSNS
B12 supplement useNSNot includedNANS
Daily B12 intake*0.28<0.001Not includedNA–0.160.001
Folic acid supplement useNot includedNA0.18<0.01NS
Daily folate intake*Not includedNA0.33<0.001NS
Serum B12*NS−0.20<0.001
Serum folate*NS−0.35<0.001
  • *Log transformed for statistical comparison.

  • –, Tested but not significant in the model;

  • BMI, body mass index; NA, not applicable; NS, not significant; TC:HDL, total cholesterol:high-density lipoprotein ratio.