Follow-up schedule
| Enrolment | Postallocation—treatment period | ||||
|---|---|---|---|---|---|
| Before treatment (up to 30 days prior to baseline) | Allocation Week 0, day 1 | Weeks 1–4 (±3 days) | After 6 weeks (±7 days) | After 24 and 48 weeks (±7 days) | |
| Screening of eligibility | X | ||||
| Informed consent | X | ||||
| Medical history | X | ||||
| Renal and liver function test | X | X | X | ||
| Randomised allocation | X | ||||
| Intervention (for interventional group) | X | X | X | X | |
| Standard care (for all patients) | X | X | X | X | |
| Outcome assessment (Spot urine+blood) | X | X | |||
| Adverse events | X | X | X | X | |