CV event-related costs by cohort and index event
| Cohort | Group | n | Total costs (in £) | Incremental total costs (in £) | |||
|---|---|---|---|---|---|---|---|
| Baseline (1 year before first CV event) (mean (SE)) | Months 1–6 (mean (SE)) | Months 7–36 annualised (mean (SE)) | Months 1–6 (mean (SE)) | Months 7–36 annualised (mean (SE)) | |||
| First event | Myocardial infarction | 4468 | 2266.34 (163.45) | 5297.59 (115.51) | 2350.66 (165.54) | 4275.41 (102.41) | 922.43 (155.58) |
| Unstable angina | 5801 | 1965.61 (86.76) | 3133.12 (61.44) | 2081.84 (65.15) | 2179.24 (48.51) | 328.45 (61) | |
| Ischaemic stroke | 3489 | 1962.42 (119.73) | 4389.27 (102.29) | 2526.63 (276.42) | 3512.25 (102.82) | 972.62 (257.48) | |
| PTCA/CABG* | 5082 | 2412.2 (95.69) | 6843.38 (94.67) | 1855.11 (110.02) | 5635.19 (87.29) | −368.26 (103.58) | |
| Heart failure | 3596 | 3148.72 (136.77) | 3988.86 (111.87) | 3607.86 (313.16) | 2443.58 (95.22) | 847.55 (247.64) | |
| Transient ischaemic attack | 1657 | 2109.76 (215.46) | 2488.83 (89.42) | 2362.10 (152.91) | 1536.88 (69.22) | 704.76 (147.47) | |
| All patients (hospital) | 24 093 | 1565.41 (56.72) | 4059.91 (38.39) | 1432.92 (59.15) | 3337.51 (37.75) | 203.18 (48.2) | |
| All patients (total) | 24 093 | 2301.34 (57.26) | 4594.16 (39.01) | 2262.92 (60.37) | 3504.01 (38.04) | 361.11 (48.79) | |
| Second event | Myocardial infarction | 769 | 2611.88 (326.29) | 5785.47 (353.52) | 3887.74 (909.42) | 4301.01 (330.02) | 1384.51 (622.14) |
| Unstable angina | 1347 | 2795.44 (398.16) | 3925.66 (204.31) | 2844.49 (247.33) | 2489.48 (132.63) | 676.82 (278.78) | |
| Ischaemic stroke | 532 | 2202.96 (143.98) | 5607.47 (273.97) | 2870.35 (281.51) | 4572.28 (280.27) | 682.29 (438.78) | |
| PTCA/CABG* | 1256 | 1635.76 (63.68) | 6630.29 (208.77) | 2121.06 (302.87) | 5823.12 (202.55) | 598.64 (296.25) | |
| Heart failure | 1104 | 2737.60 (97.24) | 4818.24 (318.44) | 5554.17 (1732.62) | 3460.91 (312.14) | 2829.02 (1643.39) | |
| Transient ischaemic attack | 266 | 1999.77 (142.44) | 2734.81 (183.68) | 3337.07 (814.53) | 1813.63 (187.64) | 1691.81 (790.76) | |
| All patients (hospital) | 5274 | 1588.26 (100.82) | 4530.08 (100.6) | 2061.65 (237.53) | 3736.68 (85.06) | 762.21 (237.68) | |
| All patients (total) | 5274 | 2380.42 (100.97) | 5147.79 (100.62) | 2998.11 (242.14) | 3967.74 (84.73) | 1017.68 (239.47) | |
| First and second events combined | Myocardial infarction | 5237 | 2317.12 (144.72) | 5354.01 (113.64) | 2472.28 (168.56) | 4277.23 (95.51) | 958.78 (134.53) |
| Unstable angina | 7148 | 2121.98 (111.68) | 3261.27 (65.83) | 2179.64 (75.16) | 2229.42 (50.81) | 373.15 (74.47) | |
| Ischaemic stroke | 4021 | 1994.31 (91.59) | 4533.08 (103.14) | 2545.1 (274.62) | 3637.86 (103.05) | 953.48 (261.93) | |
| PTCA/CABG* | 6338 | 2258.28 (69.8) | 6802.98 (86.73) | 1894.5 (89.56) | 5669.47 (85.13) | −220.73 (83.14) | |
| Heart failure | 4700 | 3052.04 (112.99) | 4144.89 (116.03) | 3881.8 (344.1) | 2635.35 (105.35) | 1128.86 (300.08) | |
| Transient ischaemic attack | 1923 | 2094.55 (195.16) | 2519.75 (87.9) | 2447.92 (150.36) | 1571.55 (68.74) | 792.85 (146.55) | |
| All patients (hospital) | 29 367 | 1569.51 (43.75) | 4133.76 (40.95) | 1508.48 (59.3) | 3400.25 (35.58) | 269.32 (53.9) | |
| All patients (total) | 29 367 | 2315.55 (43.78) | 4681.04 (41.45) | 2351.28 (59.09) | 3576.82 (36.18) | 438.89 (54) | |
*The proportions of revascularisation events that were CABG were 42% (2137/5082), 35% (442/1256) and 41% (2579/6338) for the first event, second event and all (combined) cohorts, respectively.
CABG, coronary artery bypass graft; CV, cardiovascular; PTCA, percutaneous transluminal coronary angioplasty.