Intervention group | Control group | |||||||
---|---|---|---|---|---|---|---|---|
MAI sum score at patient level | ni | Mi (SD) | Mediani (IQR) | nc | Mc (SD) | Medianc (IQR) | ICC/ICCadj | p Value |
T0 | 50 | 5.0 (4.69) | 3.5 (2–6.75) | 50 | 4.8 (5.40) | 3 (1–6.75) | 0.085/0.099 | 0.882 |
T1 | 48 | 5.1 (5.12) | 4 (1–7.25) | 48 | 4.2 (5.09) | 2 (0–7) | 0.000/0.000 | 0.401 |
T2 | 46 | 5.7 (6.57) | 3 (1–7) | 47 | 4.6 (4.76) | 3 (1–7) | 0.049/0.053 | 0.387 |
MAI sum score T1-T0 | 48 | 0.1 (5.31) | 0.5 (−3–3) | 48 | −0.6 (5.56) | 0 (−2.25–1.25) | 0.023/0.032 | 0.548 |
MI-MC (95% CI), not adjusted | −0.7 (−1.6 to 0.2)* | |||||||
MI-MC (95% CI), adjusted for clustering | −0.7 (−3.0 to 1.6)* | |||||||
MAI sum score T2-T0 | 46 | 0.7 (5.45) | 0 (−2–3) | 47 | −0.2 (5.17) | 0 (−2–2.5) | 0.030/0.039 | 0.460 |
MI-MC (95% CI), not adjusted | −0.9 (−1.8 to 0.1)* | |||||||
MI-MC (95% CI), adjusted for clustering | −0.9 (−3.2 to 1.4)* | |||||||
Inappropriate prescriptions per group | Numberni/Ni | Proportion% | Numbernc/Nc | Proportions% | ||||
T0 | 130/439 | 29.6 | 108/412 | 26.2 | ||||
T1 | 109/415 | 26.3 | 90/385 | 23.4 | ||||
T2 | 107/393 | 27.2 | 99/371 | 26.7 | ||||
Inappropriate prescriptions per patient | NumberMi (SD) | ProportionMi (SD) | NumberMc (SD) | ProportionMc (SD) | ||||
T0 | 2.60 (1.67) | 0.30 (0.18) | 2.16 (1.80) | 0.25 (0.19) | ||||
T1 | 2.27 (1.82) | 0.26 (0.20) | 1.875 (1.81) | 0.22 (0.20) | ||||
T2 | 2.33 (1.89) | 0.26 (0.20) | 2.11 (1.82) | 0.24 (0.20) |
If not stated otherwise, mean (M) and SD are provided. ICCs are provided as crude values and adjusted for group. p Values are adjusted for cluster effects.
*The trend was in favour of the control group.
ICC, intracluster correlation coefficient; MAI, medication appropriateness index.