Insulin resistance, pre-diabetes and type 2 diabetes among infertile Mexican women with polycystic ovary syndrome
| Characteristic | Total women n=538 | Normal weight n=83 | Overweight n=217 | Normal vs overweight p | Obese n=238 | Normal vs obese p |
|---|---|---|---|---|---|---|
| Fasting insulin (µU/mL) | 16.5±11.6 | 9.3±8.2 | 14.7±9.1 | 0.0001 | 20.6±12.9 | 0.0001 |
| Fasting glucose (mmol/L) | 5.26±0.82 | 4.82±0.44 | 5.22±0.82 | 0.0001 | 5.45±0.87 | 0.0001 |
| HOMA-IR | 4.0±3.1 | 2.06±2.0 | 3.5±2.4 | 0.001 | 5.1±3.6 | 0.0001 |
| HOMA-IR≥2.5 | 324 (60.2) | 16 (19.3) | 122 (56.2) *5.3 (2.9–9.8) | 0.0001 | 186 (78.2) *14.9 (8.0–28) | 0.0001 |
| Pre-diabetes | 119 (22.1) | 6 (7.2) | 38 (17.5) *2.7 (1.1–6.7) | 0.03 | 75 (31.5) *5.9 (2.4–14) | 0.0001 |
| Type 2 diabetes | 24 (4.5) | 1 (1.2) | 11 (5.1) *4.3 (0.5–34) | 0.23 | 12 (5) *4.3 (0.5–34) | 0.22 |
Values expressed as mean±SD and/or frequency and (proportion).
*OR (95% CI).
HOMA-IR, homeostatic model assessment of insulin resistance.