Pooled results of the remaining studies | Heterogeneity of the remaining studies | |||
---|---|---|---|---|
Exclusion of studies | SMD | p Value | I2 (%) | p Value |
Mean VAS pain score for 24 hours postoperatively | ||||
Total hip arthroplasty | −0.47 (−0.80, −0.14) | 0.005 | 69 | 0.004 |
Mixed with epinephrine | −0.58 (−0.96, −0.19) | 0.003 | 79 | <0.001 |
Poor methodological quality | −0.67 (−1.04, −0.30) | <0.001 | 64 | 0.03 |
Mean VAS pain score for 24–48 hours postoperatively | ||||
Total hip arthroplasty | −0.02 (−0.26, 0.22) | 0.86 | 0 | 0.52 |
Poor methodological quality | −0.07 (−0.28, 0.14) | 0.52 | 1 | 0.39 |
Narcotic use for 24 hours postoperatively | ||||
Total hip arthroplasty | −0.32 (−0.58, −0.05) | 0.02 | 59 | 0.02 |
Mixed with epinephrine | −0.24 (−0.49, −0.01) | 0.06 | 52 | 0.05 |
Poor methodological quality | −0.39 (−0.68, −0.09) | 0.01 | 53 | 0.06 |
Injection 24 hours postoperatively | −0.17 (−0.32,−0.02) | 0.03 | 40 | 0.11 |
Adverse effects | ||||
Total hip arthroplasty | 0.72 (0.21, 2.43) | 0.59 | 86 | <0.001 |
Mixed with epinephrine | 0.99 (0.59, 1.66) | 0.97 | 83 | <0.001 |
Poor methodological quality | 0.85 (0.40, 1.80) | 0.68 | 87 | <0.001 |
SMD, standardised mean difference; VAS, visual analogue scale.