Definitions of grade 3 and grade 4 diarrhoea and pneumonia events used for severity grading of adverse events
| Severity grade | Grade 3 | Grade 4 |
|---|---|---|
| Pneumonia | Cough plus fast breathing and intercostal recessions without central cyanosis | Cough plus fast breathing and intercostal recessions with central cyanosis |
| Diarrhoea | Frequent liquid stools with some dehydration | Frequent liquid stools with severe dehydration |