Blood tests
| Sampling period | Analysis |
|---|---|
| Baseline and every 12 weeks | Fasting plasma glucose or casual plasma glucose, HbA1c, IRI (glucose tolerance) White cell count, red blood cell, haematocrit, haemoglobin, platelet (blood counting) Natrium, potassium, chlorine, calcium, phosphorus, magnesium (serum electrolytes) LDL cholesterol, HDL cholesterol, triglycerides (lipids) AST, ALT, γ-GTP, proteins, albumin (liver function) Blood urea nitrogen, creatinine, uric acid (renal function) |
| Baseline and every 48 weeks | 75-g OGTT includes IRI (glucose tolerance) 25(OH)D (vitamin D level) |
| Baseline and at 48-week | RANKL, osteoprotegerin, osteocalcin, leptin (additional laboratory check) |
25(OH)D, 25-hydroxy vitamin D; γ-GTP, γ-glutamyl-transpeptidase; ALT, alanine aminotransferase; AST, aspartate aminotransferase; HbA1c, glycated haemoglobin; HDL, high-density lipoprotein; IRI, immunoreactive insulin; LDL, low-density lipoprotein; OGTT, oral glucose tolerance test; RANKL, receptor activator of nuclear factor κ-B ligand.