Table 1

Inclusion and exclusion criteria for the CASCADE Junior trials

Inclusion criteria	Exclusion criteria
Patients <18 years of age Will remain admitted to the Royal Children's Hospital or Lady Cilento Children's Hospital for >24 hours Informed consent to participate	All other intravascular device types (eg, totally implanted CVADs, peripheral intravascular devices) Current bloodstream infection Non-English speakers without an interpreter CVADs inserted through diseased burned, scarred or extremely diaphroetic skin Known allergy to any study product Current skin tear/‘papery’ skin at high risk of tear Previous enrolment in the CASCADE Junior studies within this hospital admission
PICC-CASCADE Junior PICC to be inserted and will remain in situ for >24 hours
nt-CASCADE Junior nt-CVAD to be inserted and will remain in situ for >24 hours
t-CASCADE Junior t-CVAD to be inserted and will remain in situ for >24 hours

CASCADE, Central venous Access device SeCurement And Dressing Effectiveness; CVAD, central venous access device; nt, non-tunnelled; PICC, peripherally inserted central catheter; t, tunnelled.