Characteristics and predictors of survival in 451 bigger babies admitted to CMJAH PNICU between 1 January 2013 and 30 June 2015
| Variable | Children with the condition (%) | Percentage of babies with the condition that died (95% CI) | Percentage of babies without the condition that died (95% CI) | p Value |
|---|---|---|---|---|
| Place of birth | ||||
| Another unit | 220 (48.7) | 34.1 (27.8 to 40.4) | 0.577 | |
| Born outside health facility | 14 (3.1) | 28.6 (4.9 to 52.3) | ||
| CMJAH | 186 (41.2) | 30.1 (23.5 to 36.7) | ||
| Antenatal care | 302 (67) | 27.2 (22.2 to 32.2) | 26.8 (18.0 to 35.6) | 0.827 |
| Maternal HIV | 127 (28.2) | 32.3 (24.2-40.4) | 24.9 (20.0-29.9) | 0.231 |
| Caesarean section | 169 (37.4) | 23.6 (17.0 to 30.2) | 32.9 (25.9 to 40.0) | 0.31 |
| Male | 274 (60.8) | 27.7 (22.4 to 33.0) | 25.3 (18.8 to 31.8) | 0.491 |
| Resuscitated at birth | 98 (21.7) | 28.6 (19.7 to 37.6) | 26.1 (21.5 to 30.7) | 0.619 |
| Early-onset sepsis | 20 (4.4) | 20 (2.5 to 37.5) | 27.1 (22.8 to 31.4) | 0.664 |
| Meconium aspiration | 75 (16.6) | 25.3 (15.5 to 35.1) | 26.9 (22.4 to 31.4) | 0.784 |
| Hyaline membrane disease* | 89 (19.7) | 16.9 (9.1 to 24.7) | 29.0 (24.3 to 33.7) | 0.02 |
| PPHN* | 45 (10.0) | 46.7 (32.1 to 61.3) | 24.4 (20.2 to 28.6) | 0.002 |
| Surfactant therapy | 108 (23.9) | 21.3 (13.4 to 29.0) | 28.7 (13.4 to 29.0) | 0.518 |
| Hypotension requiring inotropes* | 55 (12.2) | 54.5 (41.3 to 67.7) | 22.7 (18.6 to 26.8) | <0.001 |
| CHD* | 37 (8.2) | 54.1 (38.0 to 70.2) | 25.3 (21.1 to 29.5) | <0.001 |
| NEC | 43 (9.5) | 37.2 (22.8 to 51.7) | 25.3 (21.1 to 29.5) | 0.35 |
| Surgery (excluding NEC) | 129 (28.6) | 23.3 (16.0 to 30.6) | 28.0 (23.1 to 32.9) | 0.395 |
| Hyperglycaemia* | 46 (10.2) | 41.3 (27.1 to 55.5) | 24.9 (20.7 to 29.1) | 0.017 |
| Metabolic acidosis* | 48 (10.6) | 56.3 (42.3 to 70.3) | 23.1 (19.0 to 27.2) | <0.001 |
| Late-onset sepsis | 119 (26.4) | 29.4 (21.2 to 37.6) | 25.6 (20.9 to 30.3) | 0.420 |
| Major birth defect* | 146 (32.4) | 36.3 (28.5 to 44.1) | 22.0 (17.4 to 26.7) | 0.002 |
*Statistically significant predictors of survival on univariate analysis.
CHD, congenital heart disease; CMJAH, Charlotte Maxeke Johannesburg Academic Hospital; NEC, necrotising enterocolitis; PNICU, paediatric/neonatal intensive care unit; PPHN, persistent pulmonary hypertension of the neonate.