HRs and their 95% CIs from the Cox model for prediction of NAFLD using WBC as the independent variable
| Unadjusted | Model 1* | Model 2† | Model 3‡ | |
|---|---|---|---|---|
| WBC count (cells×109/L) | ||||
| <5.35 | Reference | Reference | Reference | Reference |
| 5.35–6.20 | 1.310 (1.180 to 1.454) | 1.241 (1.118 to 1.378) | 1.243 (1.116 to 1.384) | 1.090 (0.978 to 1.215) |
| 6.20–7.14 | 1.511 (1.365 to 1.673) | 1.427 (1.289 to 1.580) | 1.440 (1.296 to 1.600) | 1.174 (1.055 to 1.305) |
| ≥7.14 | 1.654 (1.497 to 1.828) | 1.507 (1.363 to 1.666) | 1.558 (1.404 to 1.729) | 1.152 (1.035 to 1.281) |
| Age | 1.019 (1.017 to 1.021) | 1.019 (1.017 to 1.021) | 1.007 (1.005 to 1.010) | |
| Gender | ||||
| Male | Reference | Reference | Reference | |
| Female | 0.618 (0.576 to 0.664) | 0.607 (0.563 to 0.654) | 0.746 (0.689 to 0.807) | |
| Regular exercise | 0.922 (0.855 to 0.995) | 0.917 (0.850 to 0.989) | ||
| BMI | 1.153 (1.138 to 1.167) | |||
| Hypertension | 1.230 (1.126 to 1.344) | |||
| TG | 1.190 (1.165 to 1.216) | |||
| HDL-C | 0.798 (0.708 to 0.899) | |||
| LDL-C | 1.192 (1.134 to 1.253) | |||
| GLO | 1.011 (1.002 to 1.020) | |||
*Adjusted by baseline age and gender.
†Adjusted by baseline age, gender, smoking and regular exercise.
‡Adjusted by baseline age, gender, smoking, regular exercise, BMI, hypertension, hyperglycaemia, TC, TG, HDL-C, LDL-C, ALB and GLO.
BMI, body mass index; GLO, globin; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; NAFLD, non-alcoholic fatty liver disease; TG, triglyceride; WBC, white blood cell count.