Patients with MI discharged in 2012: Cox regression analysis: HR for having a break in P2Y12 antagonist treatment >30 days with or without PCI
| Patients with PCI | Non-PCI patients | |||||
|---|---|---|---|---|---|---|
| Number of patients | Number of patients with breaks | HR (95% CI) | Number of patients | Number of patients with breaks | HR (95% CI) | |
| All patients | 3373 | 1513 | 1399 | 972 | ||
| Clopidogrel | 697 | 317 | Reference | 579 | 411 | Reference |
| Ticagrelor | 2164 | 937 | 1.20 (1.03 to 1.39) | 800 | 552 | 1.48 (1.27 to 1.72) |
| Prasugrel | 512 | 259 | 1.48 (1.24 to 1.78) | 20 | 9 | 0.86 (0.47 to 1.58) |
| Female | 911 | 398 | Reference | 666 | 481 | Reference |
| Male | 2462 | 1115 | 1.00 (0.88 to 1.13) | 733 | 491 | 0.91 (0.78 to 1.05) |
| <60 years | 1216 | 503 | 1.01 (0.90 to 1.14) | 277 | 168 | 1.18 (0.97 to 1.43) |
| 60 to 75 years | 1481 | 648 | Reference | 554 | 344 | Reference |
| >75 years | 676 | 362 | 1.15 (1.00 to 1.34) | 568 | 460 | 1.02 (0.86 to 1.21) |
| Local hospital | 878 | 403 | Reference | 498 | 357 | Reference |
| Main regional hospital | 1404 | 620 | 0.97 (0.85 to 1.11) | 588 | 399 | 0.99 (0.84 to 1.18) |
| Tertiary cardiac hospital | 1091 | 490 | 1.00 (0.86 to 1.15) | 313 | 216 | 1.12 (0.92 to 1.38) |
| CABG | 56 | 22 | 0.81 (0.49 to 1.34) | 191 | 107 | 1.00 (0.80 to 1.25) |
| Heart failure | 59 | 42 | 1.40 (0.94 to 2.08) | 86 | 79 | 1.33 (0.98 to 1.81) |
| Stroke | 97 | 56 | 1.34 (0.99 to 1.82) | 101 | 77 | 1.11 (0.82 to 1.49) |
| Atrial fibrillation | 92 | 68 | 1.88 (1.41 to 2.50) | 94 | 81 | 1.27 (0.95 to 1.70) |
| Diabetes | 411 | 229 | 1.23 (1.05 to 1.44) | 258 | 196 | 0.96 (0.79 to 1.16) |
| Cancer | 219 | 131 | 1.09 (0.88 to 1.34) | 125 | 104 | 1.03 (0.80 to 1.33) |
| Major bleeding | 67 | 39 | 1.07 (0.74 to 1.56) | 53 | 36 | 1.20 (0.86 to 1.67) |
| Peripheral arterial disease | 85 | 61 | 1.63 (1.20 to 2.20) | 93 | 74 | 0.99 (0.72 to 1.36) |
Local hospital, hospital without catheterisation laboratory; main regional hospital, hospital with catheterisation laboratory; tertiary cardiac hospital, university hospital with catheterisation laboratory.
CABG, coronary artery bypass graft; MI, myocardial infarction; PCI, percutaneous coronary intervention.