Table 3

Comparison between drug adherence levels obtained by our tool and other measures at the drug level (n=913 drugs)

Drug adherence levels obtained by our tool
Level 1: high adherence (n=431)Level 2: good adherence (n=104)Level 3: moderate adherence (n=153)Level 4: poor adherence (n=102)Level 5: very poor adherence (n=79)Level 6: discontinuation (n=44)p Value*
Patient-reported ability to take the medication as prescribed (Lu et al)†9.9 (0.8)9.7 (0.6)8.7 (1.6)7.9 (2.1)6.6 (3.4)2.1 (3.8)<0.01
Adherence Estimator
 Patient's evaluation of the medication's importance‡1.3 (0.8)1.4 (0.8)1.5 (0.8)1.4 (0.9)2.5 (1.7)2.5 (2.0)<0.01
 Patient’s evaluation of the medication's risk/benefit balance‡5.1 (1.5)4.8 (1.8)4.8 (1.5)5.0 (1.4)4.5 (1.8)4.5 (1.7)<0.01
 Patient’s evaluation of the medication's financial burden‡5.6 (1.2)5.4 (1.5)5.1 (1.8)4.8 (1.8)4.9 (1.8)4.7 (2.0)0.28
Physician’s perception of patient’s ability to take medication as prescribed§8.6 (1.9)8.1 (2.1)8.8 (1.8)7.6 (2.2)7.3 (2.6)6.3 (3.2)<0.01
  • Data are mean (SD).

  • *Each p value refers to the β coefficient in the corresponding linear model.

  • †Range, 0 (very poor ability) to 10 (excellent ability).

  • ‡Range, 1 (agree) to 6 (completely disagree).

  • §Range, 0 (very poor ability) to 10 (excellent ability).