Table 2

Measurements obtained at different phases of the SaMi-Trop study

Phase	Measurements
Baseline: 2013–2014	Questionnaires with sociodemographic information, social determinants of health, health-related behaviours (smoking, alcohol consumption and physical activity), self-reported comorbidities, medication use, history of previous treatment for Chagas disease, signs and symptoms, functional class (Cardiovascular Functional Class Scale)19 and quality of life (WHO-QOL-BREF)20 ECG Blood collection: immunoassays, PCR for T. cruzi, NT-ProBNP
Follow-up: 2015–2016	Questionnaires with sociodemographic information, social determinants of health, health-related behaviours, self-reported comorbidities, medication use, signs and symptoms since baseline. Functional class and quality of life Vital status, history of health service utilisation, including hospital admission^a, health literacy (Short Assessment of Health Literacy)21 ECG Echocardiogram Blood collection: NT-ProBNP

Phase

Measurements

Baseline: 2013–2014

Questionnaires with sociodemographic information, social determinants of health, health-related behaviours (smoking, alcohol consumption and physical activity), self-reported comorbidities, medication use, history of previous treatment for Chagas disease, signs and symptoms, functional class (Cardiovascular Functional Class Scale)19 and quality of life (WHO-QOL-BREF)20
ECG
Blood collection: immunoassays, PCR for T. cruzi, NT-ProBNP

Follow-up: 2015–2016

Questionnaires with sociodemographic information, social determinants of health, health-related behaviours, self-reported comorbidities, medication use, signs and symptoms since baseline. Functional class and quality of life
Vital status, history of health service utilisation, including hospital admission^a, health literacy (Short Assessment of Health Literacy)21
ECG
Echocardiogram
Blood collection: NT-ProBNP

NT-ProBNP, N-terminal of the prohormone brain natriuretic peptide; SaMi-Trop, São Paulo-Minas Gerais Tropical Medicine Research Center; T. cruzi, Trypanosoma cruzi; WHO-QOL-BREF, WHO Quality of Life-BREF.