Sex differences in clinical characteristics and aneurysm morphologies
| Characteristics | Men (n=257) | Women (n=217) | p Value |
|---|---|---|---|
| Age (years) | 54.1±11.6 | 57.5±12.8 | 0.002 |
| WFNS grade at admission | 1.7±1.3 | 1.6±1.3 | 0.692 |
| WFNS grade I–II | 204 (79.8%) | 178 (82.4%) | |
| WFNS grade III | 7 (2.7%) | 4 (1.9%) | |
| WFNS grade IV–V | 45 (17.5%) | 34 (15.7%) | |
| Fisher grade at admission | 0.380 | ||
| Grade I–II | 34 (13.2%) | 26 (12.0%) | |
| Grade III | 80 (31.1%) | 55 (25.2%) | |
| Grade IV | 123 (47.9%) | 121 (55.8%) | |
| Missing | 20 (7.8%) | 15 (7.0%) | |
| Aneurysm morphology | |||
| Vessel size (mm) | 1.8±0.6 | 2.0±0.5 | 0.002 |
| Aneurysm size (mm) | 5.6±2.6 | 4.9±2.3 | 0.001 |
| Aneurysm height (mm) | 4.5±2.2 | 4.0±2.1 | 0.011 |
| Perpendicular height (mm) | 3.7±1.8 | 3.4±1.8 | 0.107 |
| Neck size (mm) | 3.0±1.1 | 2.9±1.2 | 0.245 |
| Size ratio | 2.9±2.7 | 2.1±1.3 | <0.001 |
| Aspect ratio | 1.3±0.8 | 1.2±0.6 | 0.306 |
| Flow angle | 137.0±27.9 | 132.1±27.3 | 0.047 |
| Vessel angle | 62.5±26.5 | 57.5±28.4 | 0.046 |
| Aneurysm angle | 70.1±19.4 | 70.9±17.4 | 0.609 |
| Aneurysm projection | 0.858 | ||
| Anterior projection | 189 (73.5%) | 158 (72.8%) | |
| Posterior projection | 68 (26.5%) | 59 (27.2%) | |
| A1 segment configuration | 0.497 | ||
| Symmetric | 77 (30.0%) | 76 (35.0%) | |
| Dominant | 115 (44.7%) | 89 (41.0%) | |
| Complete | 65 (25.3%) | 52 (24.0%) | |
| Multiple aneurysms | 31 (12.1%) | 38 (17.6%) | 0.094 |
| Treatment modality | 0.883 | ||
| Clipping | 96 (37.4%) | 77 (35.5%) | |
| Coiling | 124 (48.2%) | 106 (48.8%) | |
| Medical treatment | 37 (14.4%) | 34 (15.7%) | |
| Angiographic vasospasm | 21 (8.2%) | 24 (11.1%) | 0.291 |
| Cerebral infarction | 24 (9.3%) | 25 (11.5%) | 0.437 |
WFNS, World Federation of Neurological Societies.