Table 3

Prenatal diagnosis of live births with CHD according to maternal characteristics in the EPICARD study

Prenatal diagnosis
All CHDIsolated CHD*
NPer centOR95% CIp Value†Adjusted OR‡95% CIp Value†NPer centOR95% CIp Value†Adjusted OR‡95% CIp Value†
234819.517.9 to 21.1188517.515.8 to 19.2
Age (year)
 <2526420.81.20.9 to 1.70.0041.00.7 to 1.50.0520417.71.00.7 to 1.50.620.80.5 to 1.40.44
 25–34140918.0RefRef118317.1RefRef
 35–3733418.01.00.7 to 1.41.10.7 to 1.526517.01.00.7 to 1.41.10.7 to 1.6
 >3732226.71.71.3 to 2.21.61.1 to 2.221720.71.30.9 to 1.81.30.9 to 2.0
Occupation
 Professional52417.6RefRef0.07RefRef0.3744116.3RefRef0.09RefRef0.33
 Intermediate42620.41.20.9 to 1.71.20.8 to 1.736719.41.20.9 to 1.81.10.8 to 1.7
 Administrative/Public service26815.70.90.6 to 1.30.80.5 to 1.222512.40.70.5 to 1.20.70.4 to 1.1
 Other36621.01.30.9 to 1.81.10.7 to 1.627319.11.20.8 to 1.81.10.7 to 1.7
 None62122.91.41.0 to 1.910.7 to 1.546520.41.30.9 to 1.81.00.7 to 1.7
Geographic origin
 France112917.5RefRef0.03RefRef0.6895816.3RefRef0.44RefRef0.96
 North African45521.81.31.0 to 1.71.10.8 to 1.634217.81.10.8 to 1.51.00.6 to 1.5
 Other African31524.11.51.1 to 2.01.30.8 to 1.923220.31.30.9 to 1.91.10.7 to 1.8
 Other origins43719.21.10.8 to 1.51.00.7 to 1.434319.01.20.9 to 1.71.00.7 to 1.5
Department of residence
 Paris79418.6RefRef0.04RefRef0.1065716.1RefRef0.34RefRef0.50
 Hauts-de-Seine59820.21.10.8 to 1.41.10.8 to 1.648717.71.10.8 to 1.51.20.8 to 1.7
 Seine-Saint-Denis54422.81.31.0 to 1.71.00.7 to 1.339920.31.31.0 to 1.81.10.8 to 1.6
 Val-de-Marne41215.50.80.6 to 1.10.70.5 to 1.034216.41.00.7 to 1.50.90.6 to 1.3

  • *Isolated CHD: excluding chromosomal or other anomalies.

  • †p Value of the Wald test.

  • ‡Adjusted OR for age, geographic origin, occupation, department of residence and categories of CHD (ACC-CHD33).

  • ACC, anatomic and clinical classification; CHD, congenital heart defects; EPICARD, EPIdémiologie des CARDiopathies congénitales.