Table 1

Comparison of different antiplatelet regimens for the secondary prevention of serious vascular events

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  • A, aspirin; A2, aspirin (75–160 mg) daily; A1, aspirin (30–50 mg) daily; A3, aspirin (283–330 mg) daily; A4, aspirin (500–1500 mg) daily; AD1, aspirin (50 mg) plus dipyridamole (400 mg) daily; AD2, aspirin (990–1300 mg) plus dipyridamole (150–300 mg) daily. Comparisons between regimens should be read from right to left. The top half of the table shows the results of direct comparisons (ORs and 95% CIs), whereas the bottom half shows the results of network meta-analysis (ORs and 95% credible intervals). For all data, ORs <1 favour the right regimens; to obtain ORs for comparisons in the opposite direction, reciprocals should be taken. The results for the regimens of aspirin plus cilostazol, aspirin plus ticlopidine and dipyridamole are presented in the S6 File.

  • “—” indicates that no direct comparison is available.

  • *Statistical heterogeneity was found (p-for-heterogeneity <0.1or I2>50%).