Table 1

Characteristics of study patients

CharacteristicsBefore 2009 E2 implementation (2007–2008)After 2009 E2 implementation (2009–2012)
N574 (28%)1450 (72%)
Age (mean±SD)33.64±26.3334.14±26.90
 0–15 years205 (36%)498 (34%)
 16–30 years57 (10%)157 (11%)
 31–45 years59 (10%)165 (11%)
 46–60 years115 (20%)294 (20%)
 >60 years138 (24%)336 (23%)
Gender
 Female291 (51%)734 (51%)
Health insurance*
 CSMBS112 (20%)335 (23%)
 SSS120 (21%)51 (4%)
 UC308 (54%)1001 (69%)
 Others34 (6%)63 (4%)
Charlson Comorbidity Index
 0–1371 (65%)921 (64%)
 2–3157 (27%)387 (27%)
 >344 (8%)142 (10%)
Patients eligible for
 Botulinum A toxin57 (10%)167 (12%)
 IVIG367 (64%)942 (65%)
 Leuprorelin66 (11%)131 (9%)
 Liposomal amphotericin B44 (8%)102 (7%)
 Verteporfin40 (7%)108 (7%)
  • Study patients: patients who had at least two admissions or visits during the study period, met the eligibility criteria for an E2 medicine, and who had not received an E2 medicine 1 year prior to their index visit.

  • *p<0.05.

  • CSMBS, Civil Servant Medical Benefit Scheme; SSS, Social Security Scheme.