Haematological data of 1613 Jino ethnic minority individuals with different thalassaemia subtypes
| Thalassaemia type | n | RBC (1012/L) | Hb (g/dL) | MCV (fL) | MCH (pg) | RDW (%) |
|---|---|---|---|---|---|---|
| α-Thalassaemia | 46 | 5.63±0.78 | 13.03±1.61 | 68.99±6.50 | 23.33±2.45 | 13.64±1.38 |
| α0/α | 34 | 5.88±0.68 | 12.98±1.62 | 65.69±2.65 | 22.08±0.81 | 14.01±1.37 |
| α+/α | 11 | 4.86±0.58 | 13.19±1.70 | 78.96±4.43 | 27.14±1.87 | 12.52±0.74 |
| α+/α+ | 1 | 5.34 | 12.7 | 71.5 | 23.8 | 13.1 |
| β-Thalassaemia | 144 | 5.27±0.48 | 13.31±1.70 | 72.46±7.09 | 25.29±2.75 | 13.21±0.96 |
| β0/βA | 20 | 5.41±0.38 | 10.68±0.53 | 58.70±2.31 | 19.77±0.83 | 14.23±0.40 |
| βE/βA | 120 | 5.23±0.48 | 13.77±1.41 | 75.17±3.88 | 26.34±1.49 | 12.98±0.85 |
| βE/βE | 4 | 5.91±0.51 | 12.55±1.22 | 60.23±3.61 | 21.23±1.15 | 15.00±0.57 |
| αβ-Thalassaemia | 13 | 5.67±0.70 | 13.63±1.67 | 69.40±6.85 | 24.17±2.59 | 13.12±0.92 |
| βE/βA with α0/α | 7 | 6.02±0.69 | 13.57±1.58 | 65.94±2.82 | 22.57±1.07 | 13.66±0.71 |
| βE/βA with α+/α | 5 | 5.21±0.53 | 14.08±1.88 | 76.46±3.86 | 27.00±1.33 | 12.22±0.36 |
| βE/βE with β0/βA | 1 | 5.57 | 13.8 | 58.3 | 21.2 | 11.8 |
| Total thalassaemia | 203 | 5.38±0.60 | 13.27±1.68 | 71.48±7.08 | 24.77±2.79 | 13.30±1.08 |
| Non-thalassaemia | 1410 | 4.78±0.51 | 14.21±1.67 | 85.14±6.64 | 29.85±2.79 | 12.68±1.30 |
| p Value* | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | |
| p Value† | 0.0012 | >0.05 | 0.0111 | 0.0002 | 0.0573 |
Data are shown as n, mean±SD, or raw data when necessary.
*Non-thalassaemic individuals compared with thalassaemia group.
†Compared among three subgroups of thalassaemia (α-Thal, β-Thal and αβ-Thal).
Hb, haemoglobin; MCH, mean corpuscular haemoglobin; MCV, mean corpuscular volume; RBC, red blood cell; RDW, red cell distribution width.