Distribution of general characteristics, stroke risk factors and covariates by age group and weight group based on body mass index (n=2057)*
| Variables | Underweight (n=86) | Normal (n=616) | Overweight (n=590) | Obese (n=670) | Extremely obese (n=95) |
|---|---|---|---|---|---|
| <65 years old (n=925) | n=24 | n=225 | n=274 | n=344 | n=58 |
| Body mass index† | 17.2±1.12 | 21.0±1.01 | 23.5±0.50 | 26.4±1.29 | 32.0±2.87 |
| Age, years† | 52.0±9.18 | 53.7±8.44 | 56.1±7.07 | 53.9±8.04 | 50.5±10.1 |
| Gender, male | 54.1 | 67.5 | 73.3 | 70.6 | 74.1 |
| Smoking | |||||
| Ex | 4.2 | 12.0 | 12.4 | 13.9 | 15.5 |
| Current | 54.1 | 44.4 | 47.0 | 33.3 | 36.2 |
| Drinking, current | 54.1 | 47.1 | 50.7 | 52.3 | 50.0 |
| Education | |||||
| College/university | 33.3 | 31.2 | 23.0 | 32.7 | 29.8 |
| Middle/high school | 58.3 | 58.8 | 61.2 | 56.8 | 54.4 |
| Elementary | 8.4 | 10.0 | 15.8 | 10.5 | 15.8 |
| Hypertension† | 58.3 | 68.0 | 77.3 | 88.6 | 84.4 |
| Diabetes mellitus | 50.0 | 42.2 | 48.5 | 52.9 | 60.3 |
| Dyslipidaemia† | 25.0 | 30.2 | 45.2 | 43.3 | 55.1 |
| CKD‡ | 16.6 | 3.5 | 3.6 | 5.3 | 8.6 |
| Taking a medicine, yes | |||||
| Anti-hypertensive agent† | 29.1 | 22.2 | 35.4 | 37.7 | 37.9 |
| Anti-DM agent | 20.8 | 11.1 | 13.8 | 17.4 | 17.2 |
| Lipid lowering agent | 0.0 | 4.4 | 8.0 | 8.7 | 8.6 |
| SBP, mm Hg† | 131.9±23.8 | 144.7±27.0 | 147.9±27.8 | 154.4±27.4 | 156.8±37.2 |
| DBP, mm Hg† | 79.5±14.9 | 85.1±16.1 | 87.4±14.7 | 90.1±17.1 | 90.8±24.6 |
| FBS, mg/dL | 139.9±68.1 | 140.9±80.2 | 137.3±56.8 | 143.5±60.5 | 158.3±78.6 |
| TC, mg/dL‡ | 172.1±36.0 | 181.1±43.4 | 188.2±44.5 | 193.7±47.6 | 197.7±47.4 |
| TG, mg/dL‡ | 128.9±152.4 | 117.8±79.4 | 139.4±102.6 | 154.5±112.4 | 163.4±124.1 |
| HDL, mg/dL‡ | 47.5±18.5 | 48.4±15.0 | 46.0±11.4 | 45.0±12.9 | 43.4±10.9 |
| LDL, mg/dL† | 95.9±25.0 | 108.8±35.9 | 122.2±44.5 | 121.6±37.2 | 136.4±85.9 |
| Creatinine, mg/dL | 1.06±1.10 | 0.90±1.24 | 0.87±0.62 | 0.86±0.45 | 0.99±0.86 |
| eGFR, mL/min/1.73 m2 | 93.2±32.1 | 96.8±19.1 | 94.1±17.9 | 94.1±19.6 | 93.9±23.3 |
| FIM, discharge | 94.8±31.6 | 105.7±22.3 | 105.6±23.3 | 106.7±23.0 | 106.4±26.1 |
| FIM, 6 months‡ | 108.4±27.3 | 118.1±16.2 | 116.7±20.5 | 118.9±18.1 | 120.6±16.1 |
| NIHSS, 7-day | 4.38±5.68 | 3.16±5.01 | 2.94±4.80 | 2.55±4.36 | 2.40±3.74 |
| ≥65 years old (n=1132) | n=62 | n=391 | n=316 | n=326 | n=37 |
| Body mass index† | 17.4±0.90 | 20.8±1.05 | 23.5±0.50 | 26.2±1.26 | 31.7±2.67 |
| Age, years† | 79.1±5.65 | 75.7±6.20 | 74.3±5.57 | 73.6±5.66 | 72.6±5.35 |
| Gender, male‡ | 35.4 | 58.8 | 58.8 | 55.5 | 45.9 |
| Smoking | |||||
| Ex | 14.5 | 17.1 | 18.6 | 18.7 | 13.5 |
| Current | 19.3 | 19.4 | 16.1 | 16.2 | 5.4 |
| Drinking, current | 19.3 | 31.2 | 24.0 | 32.2 | 27.0 |
| Education | |||||
| College/university | 1.6 | 10.8 | 12.9 | 12.8 | 18.9 |
| Middle/high school | 47.5 | 36.5 | 39.7 | 42.8 | 32.4 |
| Elementary | 50.9 | 52.7 | 47.4 | 44.4 | 48.7 |
| Hypertension‡ | 85.4 | 87.2 | 86.7 | 92.9 | 97.3 |
| Diabetes mellitus | 46.7 | 53.2 | 56.6 | 57.6 | 67.5 |
| Dyslipidaemia | 20.9 | 28.9 | 31.3 | 32.2 | 37.8 |
| CKD | 29.5 | 16.7 | 20.1 | 18.6 | 16.6 |
| Taking a medicine, yes | |||||
| Anti-hypertensive agent† | 32.2 | 51.9 | 51.5 | 60.7 | 83.7 |
| Anti-DM agent | 19.3 | 23.7 | 21.5 | 27.6 | 40.5 |
| Lipid lowering agent‡ | 4.8 | 8.4 | 14.8 | 12.8 | 18.9 |
| SBP, mm Hg | 152.2±32.0 | 148.9±25.4 | 148.1±28.8 | 151.2±26.2 | 148.6±25.9 |
| DBP, mm Hg | 81.0±18.9 | 82.0±12.9 | 82.0±14.4 | 83.2±14.5 | 81.0±12.9 |
| FBS, mg/dL | 138.7±67.2 | 142.2±65.8 | 144.3±65.7 | 143.4±56.6 | 136.5±44.6 |
| TC, mg/dL | 176.5±43.0 | 174.3±39.2 | 176.0±37.0 | 175.7±41.7 | 172.9±49.1 |
| TG, mg/dL† | 88.1±41.8 | 104.8±63.2 | 111.6±60.8 | 127.3±77.6 | 113.6±60.1 |
| HDL, mg/dL† | 50.6±13.7 | 47.4±13.2 | 44.9±13.3 | 43.4±11.2 | 48.7±11.6 |
| LDL, mg/dL | 110.2±46.2 | 107.6±33.4 | 109.1±32.8 | 110.4±46.2 | 112.5±36.5 |
| Creatinine, mg/dL | 1.09±1.72 | 1.08±1.48 | 0.95±0.57 | 0.94±0.40 | 0.86±0.29 |
| eGFR, mL/min/1.73 m2 | 72.4±21.3 | 75.9±20.3 | 75.6±18.8 | 74.3±17.9 | 77.4±16.8 |
| FIM, discharge | 81.8±32.8 | 89.3±31.4 | 93.1±31.2 | 95.4±29.3 | 93.1±31.7 |
| FIM, 6 months | 93.0±38.4 | 100.4±33.2 | 104.2±32.0 | 106.5±29.7 | 111.6±27.8 |
| NIHSS, 7-day‡ | 4.95±5.89 | 4.67±6.06 | 4.08±6.08 | 3.49±5.48 | 3.76±7.82 |
†p<0.001; ‡p<0.05.
*Analysis of variance or χ2 test.
CKD, chronic kidney disease; DBP, diastolic blood pressure; DM, diabetes mellitus; eGFR, estimated glomerular filtration rate; FBS, fasting blood sugar; FIM, functional independence measure; HDL, high density lipoprotein; LDL, low density lipoprotein; NIHSS, National Institutes of Health Stroke Scale; SBP, systolic blood pressure; TC, total cholesterol; TG, triglyceride.