Stratified associations between adjustment disorder and CVD events, Denmark, 1995–2011
| CVD events | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Myocardial infarction | Stroke | Ischaemic stroke | Venous thromboembolism | |||||||||
| O | E | SIR (95% CI) | O | E | SIR (95% CI) | O | E | SIR (95% CI) | O | E | SIR (95% CI) | |
| Adjustment disorder | 803 | 550.4 | 1.5 (1.4 to 1.6) | 1483 | 839.6 | 1.8 (1.7 to 1.9) | 712 | 409.8 | 1.7 (1.6 to 1.9) | 1006 | 537.0 | 1.9 (1.8 to 2.0) |
| Gender | ||||||||||||
| Male | 422 | 292.3 | 1.4 (1.3 to 1.6) | 614 | 333.2 | 1.8 (1.7 to 2.0) | 313 | 169.1 | 1.9 (1.7 to 2.1) | 373 | 181.6 | 2.1 (1.9 to 2.3) |
| Female | 381 | 258.1 | 1.5 (1.3 to 1.6) | 869 | 506.4 | 1.7 (1.6 to 1.8) | 399 | 240.7 | 1.7 (1.5 to 1.8) | 633 | 355.4 | 1.8 (1.7 to 1.9) |
| Age at adjustment disorder diagnosis (years) | ||||||||||||
| 16–39 | 156 | 76.5 | 2.1 (1.7 to 2.4) | 290 | 121.1 | 2.4 (2.1 to 2.7) | 139 | 61.5 | 2.3 (1.9 to 2.7) | 427 | 189.1 | 2.3 (2.1 to 2.5) |
| 40–59 | 386 | 260.3 | 1.5 (1.3 to 1.6) | 719 | 354.6 | 2.0 (1.9 to 2.2) | 370 | 184.4 | 2.0 (1.8 to 2.2) | 399 | 216.7 | 1.8 (1.7 to 2.0) |
| 60+ | 261 | 213.5 | 1.2 (1.1 to 1.4) | 474 | 363.9 | 1.3 (1.2 to 1.4) | 203 | 163.8 | 1.2 (1.1 to 1.4) | 180 | 131.2 | 1.4 (1.2 to 1.6) |
| Depression diagnoses | ||||||||||||
| Yes | 86 | 52.3 | 1.6 (1.3 to 2.0) | 161 | 84.6 | 1.9 (1.6 to 2.2) | 79 | 40.3 | 2.0 (1.6 to 2.4) | 90 | 41.4 | 2.2 (1.8 to 2.7) |
| No | 717 | 498.1 | 1.4 (1.3 to 1.6) | 1322 | 755.0 | 1.8 (1.7 to 1.9) | 633 | 369.5 | 1.7 (1.6 to 1.9) | 916 | 495.6 | 1.9 (1.7 to 2.0) |
| Alcohol diagnoses | ||||||||||||
| Yes | 66 | 35.6 | 1.9 (1.4 to 2.4) | 168 | 45.3 | 3.7 (3.2 to 4.3) | 80 | 23.4 | 3.4 (2.7 to 4.3) | 86 | 27.2 | 3.2 (2.5 to 3.9) |
| No | 737 | 514.8 | 1.4 (1.3 to 1.5) | 1315 | 794.3 | 1.7 (1.6 to 1.8) | 632 | 386.4 | 1.6 (1.5 to 1.8) | 920 | 509.8 | 1.8 (1.7 to 1.9) |
| CCI score | ||||||||||||
| 0 | 550 | 425.0 | 1.3 (1.2 to 1.4) | 1051 | 641.4 | 1.6 (1.6 to 1.7) | 512 | 316.0 | 1.6 (1.5 to 1.8) | 781 | 437.7 | 1.8 (1.7 to 1.9) |
| 1+ | 253 | 125.3 | 2.0 (1.8 to 2.3) | 432 | 198.2 | 2.2 (2.0 to 2.4) | 200 | 93.8 | 2.1 (1.9 to 2.5) | 225 | 99.2 | 2.3 (2.0 to 2.6) |
| Follow-up time (years) | ||||||||||||
| 1 to <5 | 297 | 218.3 | 1.4 (1.2 to 1.5) | 597 | 334.7 | 1.8 (1.6 to 1.9) | 271 | 146.2 | 1.9 (1.6 to 2.1) | 409 | 203.6 | 2.0 (1.8 to 2.2) |
| 5 to <10 | 308 | 196.5 | 1.6 (1.4 to 1.8) | 510 | 299.5 | 1.7 (1.6 to 1.9) | 232 | 146.4 | 1.6 (1.4 to 1.8) | 350 | 192.6 | 1.8 (1.6 to 2.0) |
| 10+ | 198 | 135.6 | 1.5 (1.3 to 1.7) | 376 | 205.5 | 1.8 (1.7 to 2.0) | 209 | 117.3 | 1.8 (1.6 to 2.0) | 247 | 140.7 | 1.8 (1.5 to 2.0) |
CCI, Charlson Comorbidity Index; CVD, cardiovascular disease; SIR, standardised incidence rate.