Multilevel logistic regression model—current record for measurement of cholesterol (DO1) in the past 15 months and demographic, risk factor and treatment with statin characteristics
| Variable | Category | Total N | DO1: N (%) | Adjusted OR (95% confidence limits) | p Value |
|---|---|---|---|---|---|
| Age (years) (n=7841) | 16–44 | 333 | 147 (44) | 1.68 (1.14 to 2.47) | 0.008 |
| 45–54 | 840 | 170 (20) | 1.50 (1.13 to 1.98) | 0.005 | |
| 55–64 | 1340 | 190 (14) | 1.45 (1.13 to1.87) | 0.004 | |
| 65–74 | 2035 | 189 (9) | Ref | ||
| 75+ | 3293 | 433 (13) | 1.41 (1.13 to 1.75) | 0.002 | |
| Sex (n=7869) | Male | 4547 | 663 (15) | Ref | |
| Female | 3322 | 494 (15) | 0.90 (0.76 to 1.06) | 0.220 | |
| Ethnicity (n=7869) | White group | 4361 | 643 (15) | Ref | |
| Black/Black British | 1616 | 197 (12) | 0.78 (0.62 to 0.97) | 0.029 | |
| Asian/Asian British | 694 | 82 (12) | 1.07 (0.78 to 1.47) | 0.6736 | |
| Mixed groups | 212 | 38 (18) | 1.07 (0.67 to 1.72) | 0.769 | |
| Other ethnic groups | 193 | 28 (15) | 1.18 (0.72 to 1.93) | 0.5010 | |
| Not known/missing | 793 | 169 (21) | 1.18 (0.90 to 1.54) | 0.231 | |
| Deprivation—Index of Multiple Deprivation national ranking (n=7824) | Least deprived | 195 | 22 (11) | Ref | |
| 40–60% | 976 | 153 (16) | 1.46 (0.76 to 2.79) | 0.254 | |
| 60–80% | 3816 | 538 (14) | 1.49 (0.80 to 2.78) | 0.210 | |
| Most deprived | 2837 | 438 (15) | 1.59 (0.85 to 2.99) | 0.147 | |
| Smoking (7869) | Non-smoker | 4146 | 579 (14) | Ref | |
| Ex-smoker | 2191 | 266 (12) | 1.07 (0.88 to 1.30) | 0.514 | |
| Current Smoker | 1456 | 271 (19) | 1.40 (1.13 to 1.74) | 0.002 | |
| Unknown | 76 | 41 (54) | 1.54 (0.51 to 4.63) | 0.440 | |
| Blood pressure (n=7786) | ≤150/90 mm Hg | 5604 | 742 (13) | Ref | |
| >150/90 mm Hg | 2182 | 343 (16) | 1.15 (0.96 to 1.36) | 0.123 | |
| Total cholesterol (n=7562) | ≤5 mmol/L | 5897 | 562 (10) | Ref | |
| >5 mmol/L | 1665 | 289 (17) | 1.33 (1.12 to 1.59) | 0.001 | |
| Statin prescription (n=7869) | Yes | 5891 | 547 (9) | Ref | |
| No | 1978 | 610 (31) | 2.97 (2.51 to 3.52) | <0.0001 | |
| BMI (kg/m2) (n=7181) | <18.5 | 138 | 23 (17) | 1.24 (0.75 to 2.04) | 0.403 |
| 18.5–24.9 | 1999 | 255 (13) | Ref | ||
| 25–29.9 | 2613 | 267 (10) | 0.97 (0.80 to 1.18) | 0.742 | |
| 30–39.9 | 2164 | 201 (9) | 0.94 (0.76 to 1.16) | 0.576 | |
| ≥40 | 267 | 24 (9) | 0.94 (0.59 to 1.50) | 0.801 | |
| Type 2 diabetes (n=7869) | Yes | 2104 | 111 (5) | 0.37 (0.29 to 0.47) | <0.0001 |
| No | 5765 | 1046 (18) | Ref | ||
| Practice-level variance | 0.12 (0.06 to 0.25) |
Logistic model for current record for cholesterol in the past 15 months, goodness-of-fit test; number of observations=7135; number of groups=10; Hosmer-Lemeshow χ2 (8)=5.74; probability > χ2=0.676; likelihood ratio test for testing multilevel logistic regression model compared with conventional logistic regression model p value <0.0001.
BMI, body mass index.