Adjusted relative risks and 95% CIs of covariates using 40 imputed data sets
| Asthma diagnosis | Wheezing symptoms | Wheezing disorder diagnosis | Wheezing disorder treatment | |
|---|---|---|---|---|
| Birth weight (kg) | ||||
| Normal (2.5–4.0) | 1 | 1 | 1 | 1 |
| High (>4.0) | 0.95 (0.75 to 1.22) | 0.90 (0.77 to 1.04) | 0.91 (0.79 to 1.04) | 0.99 (0.89 to1.11) |
| Low (<2.5) | 1.53 (1.20 to 1.96) | 1.29 (1.10 to 1.52) | 1.29 (1.12 to 1.50) | 1.25 (1.10 to 1.42) |
| Ethnicity | ||||
| White British | 1 | 1 | 1 | 1 |
| Pakistani | 1.36 (1.11 to 1.66) | 1.26 (1.12 to 1.42) | 1.21(1.08 to 1.35) | 0.95 (0.87 to 1.05) |
| Others | 0.96 (0.74 to 1.25) | 0.93 (0.79 to 1.08) | 0.90 (0.78 to 1.04) | 0.76 (0.67 to 0.85) |
| Gender | ||||
| Male | 1 | 1 | 1 | 1 |
| Female | 0.67 (0.58 to 0.76) | 0.64 (0.59 to 0.70) | 0.66 (0.61 to 0.72) | 0.71 (0.67 to 0.76) |
| Gestational age | ||||
| Term | 1 | 1 | 1 | 1 |
| Preterm | 1.11 (0.83 to 1.48) | 1.08 (0.90 to 1.30) | 1.09 (0.92 to 1.29) | 1.16 (1.01 to 1.34) |
| Number of births | ||||
| Singleton | 1 | 1 | 1 | 1 |
| Twins | 0.68 (0.42 to 1.10) | 0.71 (0.52 to 0.97) | 0.68 (0.51 to 0.90) | 0.63 (0.49 to 0.81) |
| Triplets | – | 0.57 (0.09 to 3.60) | 0.48 (0.08 to 3.03) | 0.75 (0.22 to 2.56) |
| Maternal smoking | ||||
| No | 1 | 1 | 1 | 1 |
| Yes | 0.86 (0.70 to 1.05) | 1.10 (0.98 to 1.24) | 1.07 (0.97 to 1.19) | 1.05 (0.97 to 1.15) |
| Parity | ||||
| Primiparous | 1 | 1 | 1 | 1 |
| Multiparous | 1.04 (0.91 to 1.20) | 1.14 (1.04 to 1.24) | 1.10 (1.02 to 1.19) | 1.02 (0.95 to 1.08) |
| IMD 2010 quintile score | 0.96 (0.88 to 1.05) | 0.95 (0.90 to 1.00) | 0.95 (0.91 to 1.00) | 0.97 (0.93 to 1.00) |
Model adjusted for ethnicity, gender, gestational age, number of births, maternal smoking, parity and IMD score.
IMD, index of multiple deprivation.