Adjusted and unadjusted RRs and 95% CI for growth patterns and wheezing disorders in the BiB1000 cohort
| Unadjusted RR (95% CI; p Value) | Adjusted RR (95% CI; p Value) | |
|---|---|---|
| Age-based weight SDS | ||
| Class 2 (fast growth) | ||
| Asthma diagnosis | 0.82 (0.12 to 5.56; 0.84) | 0.81 (0.12 to 5.46; 0.83) |
| Wheezing symptom | 1.50 (0.62 to 3.56; 0.36) | 1.59 (0.68 to 3.71; 0.29) |
| Wheezing disorder diagnosis | 1.25 (0.53 to 2.97; 0.61) | 1.30 (0.56 to 3.06; 0.54) |
| Wheezing disorder treatment | 0.76 (0.27 to 2.14; 0.60) | 0.77 (0.28 to 2.17; 0.63) |
| Class 3 (slow growth) | ||
| Asthma diagnosis | 1 | 1 |
| Wheezing symptom | 0.80 (0.21 to 2.93; 0.73) | 0.72 (0.20 to 2.63; 0.29) |
| Wheezing disorder diagnosis | 0.67 (0.18 to 2.45; 0.54) | 0.60 (0.16 to 2.18; 0.44) |
| Wheezing disorder treatment | 0.81 (0.29 to 2.25; 0.68) | 0.81 (0.29 to 2.25; 0.69) |
| Visits-based weight SDS | ||
| Class 2 (inconsistent growth) | ||
| Asthma diagnosis | 1.66 (0.81 to 3.42; 0.17) | 1.47 (0.71 to 3.01; 0.30) |
| Wheezing symptom | 1.15 (0.66 to 1.99; 0.62) | 1.13 (0.66 to 1.95; 0.65) |
| Wheezing disorder diagnosis | 1.42 (0.92 to 2.19; 0.11) | 1.38 (0.90 to 2.12; 0.14) |
| Wheezing disorder treatment | 1.14 (0.74 to 1.76; 0.55) | 1.17 (0.76 to 1.81; 0.47) |
Both models were adjusted for birth weight, ethnicity, gender, maternal smoking, parity and maternal SES; class 1 was a reference group in both models.
BiB, Born in Bradford; RR, relative risk; SDS, standardised scores; SES, socioeconomic status.