AFS cohort | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Birth outcomes for those using | |||||||||||
Australian reference data10 | Cannabis (with or without cigarettes) | Cigarettes only | Neither | ||||||||
Full cohort | (20.5%) | (31.9%) | (47.6%) | ||||||||
Mean | N | Mean | (SD) | Mean | (SD) | Mean | (SD) | Mean | (SD) | p Value* | |
Gestational age (weeks) | 38.8% | 308 | 38.7%† | 2.7% | 37.8% | 3.8% | 39.0% | 2.0% | 38.9% | 2.3% | 0.014 |
Birth weight (g) | 3367 | 315 | 3209‡ | 698 | 2781 | 733 | 3267 | 579 | 3345 | 690 | <0.001 |
N | |||||||||||
Gestation at birth | |||||||||||
Preterm (<37 weeks) | 8.5% | 36 | 11.7%§ | 19.1% | 8.3% | 10.7% | 0.245 | ||||
Term (≥37 and <42 weeks) | 90.9% | 268 | 87.0% | 79.4% | 89.6% | 88.6% | |||||
Post-term (≥42 weeks) | 0.6% | 4 | 1.3% | 1.6% | 2.1% | 0.7% | |||||
Infant birth weight | |||||||||||
Low (<2500 g) | 6.2% | 43 | 13.7%¶ | 35.5% | 9.1% | 7.8% | <0.001 | ||||
Appropriate (≥2500 and <4000 g) | 82.3% | 241 | 76.5% | 59.7% | 81.8% | 79.9% | |||||
High (≥4000 g) | 11.5% | 31 | 9.8% | 4.8% | 9.1% | 12.3% | |||||
Weight for gestational age | |||||||||||
Small (<10th centile) | 10.0% | 64 | 21.6%** | 38.6% | 22.6% | 14.3% | 0.004 | ||||
Appropriate (≥10th and <90th centile) | 80.0% | 210 | 70.7% | 54.4% | 72.0% | 76.2% | |||||
Large (≥90th centile) | 10.0% | 23 | 7.7% | 7.0% | 5.4% | 9.5% |
*p Value comparing mothers who used cannabis, cigarettes or neither during pregnancy (Wald test from linear regression for continuous birth outcomes, χ2 test for categorised birth outcomes).
†p Value from one sample t test comparing mean gestational age to full cohort to Australian reference data=0.498.
‡p Value from one sample t test comparing mean birth weight to Australian reference data <0.001.
§p Value from binomial probability test comparing proportion of preterm births to Australian reference data=0.052.
¶p Value from binomial probability test comparing proportion of low birth weight to Australian reference data <0.001.
**p Value from binomial probability test comparing proportion SGA to Australian reference data <0.001.