Mean age in years at first visit in 1999 | 72.5 (56–100) |
Percentage ≤high school | 34.1 |
Percentage white | 98.0 |
Percentage with CHD/stroke/diabetes before 1999 | 33.3 |
Smoking in pack-years | 21.8 (0–131) |
Anxiety | 0.2 (0–2.83) |
Depression | 0.2 (0–3.33) |
Hostility | 0.2 (0–3.00) |
Happiness | 7.4 (1–9) |
Life satisfaction | 7.9 (0–11) |
Percentage basophils | 0.6 (0–2) |
Percentage eosinophils | 3.2 (0–22) |
Percentage lymphocytes | 26.0 (5–90) |
Percentage monocytes | 8.8 (0–17) |
Percentage neutrophils | 61.65 (3–85) |
Plasma folate (ng/mL) | 17.41 (3.3–99.3) |
DNA methylation in gene promoter regions (%) | |
TLR-2 | 3.1 (0–8.9) |
F3 | 2.3 (0–14.8) |
NR3C1 | 47.0 (14.7–72.8) |
ICAM-1 | 4.4 (1.7–16.1) |
IFN-γ | 84.4 (30.9–95.7) |
IL-6 | 43.7 (10.3–86.6) |
iNOS | 69.7 (24.5–87.2) |
CHD, coronary heart disease; F3, coagulation factor III; ICAM-1, intercellular adhesion molecule-1; IFN-γ, interferon-γ; IL-6, interleukin 6; iNOS, inducible nitric oxide synthase; NR3C1, glucocorticoid receptor; TLR-2, toll-like receptor 2.