Exposed participants N=79 | Unexposed participants N=105 | Total N=184 | |
---|---|---|---|
Characteristics | Value or n (%) | Value or n (%) | Value or n (%) |
Age at 1 October 2009 | |||
Mean age (years)±SD (minimum; maximum) | 51.3±14.54 (9; 91) | 49.3±21.58 (1; 89) | 50.2±18.86 (1; 91) |
Age group at 1 October 2009 (years) | |||
(0–17) | 3 (3.8) | 9 (8.6) | 12 (6.5) |
(18–44) | 20 (25.3) | 33 (31.4) | 53 (28.8) |
(45–60) | 32 (40.5) | 31 (29.5) | 63 (34.2) |
61+ | 24 (30.4) | 32 (30.5) | 56 (30.4) |
Gender | |||
Female | 33 (41.8) | 51 (48.6) | 84 (45.7) |
Male | 46 (58.2) | 54 (51.4) | 100 (54.3) |
Number of rejections between 4 April 2009 and 1 October 2009 | |||
None | 70 (88.6) | 91 (86.7) | 161 (87.5) |
At least one | 9 (11.4) | 14 (13.3) | 23 (12.5) |
Organs transplanted before or during the study period* | |||
Heart | 1 (1.3) | 0 (0.0) | 1 (0.5) |
Kidney | 9 (11.4) | 10 (9.5) | 19 (10.3) |
Kidney and liver | 0 (0.0) | 2 (1.9) | 2 (1.1) |
Kidney and pancreas | 2 (2.5) | 0 (0.0) | 2 (1.1) |
Liver | 3 (3.8) | 6 (5.7) | 9 (4.9) |
Lung | 2 (2.5) | 0 (0.0) | 2 (1.1) |
Pancreas | 1 (1.3) | 0 (0.0) | 1 (0.5) |
No transplantation recorded | 61 (77.2) | 87 (82.9) | 148 (80.4) |
Organs rejected before or during the study period* | |||
Heart | 4 (5.1) | 4 (3.8) | 8 (4.3) |
Kidney | 56 (70.9) | 39 (37.1) | 95 (51.6) |
Kidney and liver | 0 (0.0) | 1 (1.0) | 1 (0.5) |
Kidney and pancreas | 1 (1.3) | 0 (0.0) | 1 (0.5) |
Liver | 7 (8.9) | 11 (10.5) | 18 (9.8) |
Lung | 4 (5.1) | 1 (1.0) | 5 (2.7) |
Unspecified | 7 (8.9) | 49 (46.7) | 56 (30.4) |
Number of transplantations between 1 October 2009 and 31 October 2010 | |||
0 | 67 (84.8) | 89 (84.8) | 156 (84.8) |
1 | 11 (13.9) | 13 (12.4) | 24 (13.0) |
2 | 1 (1.3) | 2 (1.9) | 3 (1.6) |
4 | 0 (0.0) | 1 (1.0) | 1 (0.5) |
Respiratory infection(s) between 1 September 2009 and 31 October 2010 | |||
No | 77 (97.5) | 105 (100) | 182 (98.9) |
Yes | 2 (2.5) | 0 (0.0) | 2 (1.1) |
Acute bacterial infection(s) between 1 September 2009 and 31 October 2010 | |||
No | 79 (100.0) | 105 (100.0) | 184 (100.0) |
Yes | 0 (0.0) | 0 (0.0) | 0 (0.0) |
Opportunistic infection(s) between 1 September 2009 and 31 October 2010 | |||
No | 73 (92.4) | 103 (98.1) | 176 (95.7) |
Yes | 6 (7.6) | 2 (1.9) | 8 (4.3) |
Chronic viral infection(s) between 1 October 2008 and 31 October 2010 | |||
No | 79 (100.0) | 105 (100.0) | 184 (100.0) |
Yes | 0 (0.0) | 0 (0.0) | 0 (0.0) |
Malignancy/cancer(s) between 01 October 2008 and 31 October 2010 | |||
No | 70 (88.6) | 99 (94.3) | 169 (91.8) |
Yes | 9 (11.4) | 6 (5.7) | 15 (8.2) |
Reasons for end of follow-up | |||
End of study period (31 October 2010) | 74 (93.7) | 94 (89.5) | 168 (91.3) |
Death | 4 (5.1) | 6 (5.7) | 10 (5.4) |
End of CRPD follow-up | 1 (1.3) | 5 (4.8) | 6 (3.3) |
*Each participant is classified in one category. All combinations are possible. Only transplantations and rejections between 4 April 2009 and 31 October 2010 are taken into account (see figure 1 for details of the various periods).
CPRD, Clinical Practice Research Datalink; n (%), number (percentage) of patients in the specified category; N, total number of patients; SOT, solid organ transplant.