Abstract
Fifty patients with essential hypertension WHO Grades I-II have been treated for 3 months with bisoprolol, a new selective beta blocker, in doses up to 40 mg once daily. Forty-three patients reached the preset target diastolic blood pressure of less than or equal to 90 mmHg on a mean daily dose of 16.8 mg bisoprolol. There was no effect on serum lipids and HDL-cholesterol during the study. The side-effects were mild and were those usually associated with beta-blocking therapy.
MeSH terms
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Adrenergic beta-Antagonists / adverse effects
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Adrenergic beta-Antagonists / pharmacology*
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Adrenergic beta-Antagonists / therapeutic use
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Adult
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Bisoprolol
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Blood Pressure / drug effects*
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Cholesterol, HDL / blood*
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Female
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Humans
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Hypertension / blood*
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Hypertension / drug therapy
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Hypertension / physiopathology
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Lipids / blood*
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Male
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Middle Aged
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Propanolamines / adverse effects
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Propanolamines / pharmacology*
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Propanolamines / therapeutic use
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Triglycerides / blood
Substances
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Adrenergic beta-Antagonists
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Cholesterol, HDL
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Lipids
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Propanolamines
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Triglycerides
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Bisoprolol