Iron status as measured by serum ferritin: The marker and its limitations
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Narrative Review of Hyperferritinemia, Iron Deficiency, and the Challenges of Managing Anemia in Aboriginal and Torres Strait Islander Australians With CKD
2021, Kidney International ReportsCitation Excerpt :There are no recommendations to vary targets according to ethnic groups. Low serum ferritin is a marker of iron deficiency.24,32,74,77,78 However, as an acute-phase protein, increased serum ferritin concentration, along with increases in other acute-phase reactants such as CRP, is observed in patients who have inflammation.35,67,79
Iron status at opposite ends of the menstrual function spectrum
2019, Journal of Trace Elements in Medicine and BiologyThermodynamics of proton binding and weak (Cl<sup>-</sup>, Na<sup>+</sup> and K<sup>+</sup>) species formation, and activity coefficients of 1,2-dimethyl-3-hydroxypyridin-4-one (deferiprone)
2014, Journal of Chemical ThermodynamicsCitation Excerpt :Moreover deferiprone may be used in the detoxification of other metals, such as aluminium, plutonium, uranium, and in the treatment of copper overloading conditions (Wilson’s disease) [3,4,9]. Commercially deferiprone is known as Ferriprox ®, clinical studies have demonstrated that this drug is effective in promoting iron excretion and can lower serum ferritin [10] and iron stores in tissues of transfusion dependent thalassaemia patients (the precise mechanism is unknown). It is rapidly absorbed from the gastrointestinal tract and is eliminated via the kidneys, mainly in the form of glucuronide metabolite and iron-deferiprone complex.
Rethinking Iron Regulation and Assessment in Iron Deficiency, Anemia of Chronic Disease, and Obesity: Introducing Hepcidin
2012, Journal of the Academy of Nutrition and DieteticsCitation Excerpt :When ACD and ID/IDA coexist, ferritin levels may remain elevated secondary to the inflammatory process and can be misleading of actual cellular iron levels (see the Table) (42). Therefore, the sole use of serum ferritin to accurately assess iron status in individuals with chronic illness or inflammation is inadequate (43). However, coupling serum ferritin with the measurement of another acute phase reactant, such as C-reactive protein, can help to indicate if underlying inflammation exists and will help to explain elevated serum ferritin despite underlying ID (23).
Comparison of serum iron status in healthy foals and foals with bronchopneumonia
2023, Pferdeheilkunde