Clinical ResearchNSAIDs and Myocardial InfarctionRole of Dose Potency in the Prediction of Risk of Myocardial Infarction Associated With Nonsteroidal Anti-Inflammatory Drugs in the General Population
NSAIDs and Myocardial Infarction
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Key Words
NSAIDs
myocardial infarction
COX-2
prostacyclin
thromboxane
Abbreviations and Acronyms
CAD
coronary artery disease
CI
confidence interval
COX
cyclooxygenase
coxibs
selective inhibitors of COX-2
CV
cardiovascular
MI
myocardial infarction
NSAID
nonsteroidal anti-inflammatory drug
RR
relative risk
tNSAID
traditional nonsteroidal anti-inflammatory drug
TX
thromboxane
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The database portion (THIN) was funded by an unrestricted research grant from Pfizer to CEIFE. The corresponding author has full authorship rights to the manuscript and was not obligated to include any Pfizer comments in the submitted manuscript. The biochemistry study was supported by a grant from the European Community's Sixth Framework Program (Eicosanox, LSMH-CT-2004-005033) to Dr. Patrignani.
Copyright © 2008 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.