The many faces of corticobasal degeneration
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2018, Neurologia i Neurochirurgia PolskaCitation Excerpt :Nevertheless regarding the fact that CBS may be related to 4R pathologies such as CBD and PSP, but also Alzheimer's disease (AD) and Pick's disease which are associated with three repeats tauopathies (3R), it should be stressed that CBS may be a clinical manifestation of either 3R or 4R [7]. It should also be highlighted that AD may be related to accumulation of both 3R and 4R [7]. This is one of the aspects allowing neuropathological differentiation between CBD/PSP and frontotemporal lobar degeneration, which is related with three repeats (3R).
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