eLetters

785 e-Letters

  • Data available in Dryad
    Peter Doshi
    Data for this article has been deposited in the Dryad digital repository. Please see:

    Doshi P, Jefferson T (2013) Data from: Clinical Study Reports of randomized controlled trials - an exploratory review of previously confidential industry reports. Dryad Digital Repository. doi:10.5061/dryad.331f7 http://dx.doi.org/10.5061/dryad.331f7

    Peter Doshi
    27-Fe...
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  • Understanding public drug procurement in India: a comparative qualitative study of five Indian states
    Amit Pachal

    Pharmaceutical procurement is a specialized professional activity that requires a lot of knowledge, skill and experience. It is therefore mandatory that staff involved in key procurement and distribution positions be well trained and highly motivated, with the capability to manage the procurement process efficiently. Pharmaceutical procurement is a complex process, which involves many steps, agencies and manufacturers. E...

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  • Kidney Failure and Piperacillin - Data and Opinions
    Jens-Ulrik S. Jensen

    Dear Editor, Recently dr. Bugge and dr. Laake posted a letter in which they argue that piperacillin/tazobactam is not nephrotoxic (1). They argue that the delayed creatinine fall (corresponding to a delayed eGFR increase) observed in our trial (2), is due to the competitive inhibition of creatinine (and tazobactam) clearance. We did point this out in our discussion. Dr?s Bugge and Laake have the opinion, that this could...

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  • RE:"National survey of US primary care physicians' perspectives about causes of obesity and solutions to improve care"
    Yvette L. Rooks

    It was with great interest that I read Dr. Sara Bleich's study on primary care physicians' perspectives on treating obesity. Unfortunately, I wasn't shocked by the findings.

    Obesity is an incredibly challenging condition to treat, and when facing a crisis as great as the United States' obesity epidemic, extraordinary steps are called for.

    Primary care physicians need to be aware of the current recomme...

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  • More Data is Needed to Prove the Safety of Metformin
    Fang LIU

    Dear Editor, Metformin is the most widely used hypoglycemic agent in the world. But the application among the diabetic patients who have the chronic kidney disease(CKD) is still controversial. What gave us a pleasant surprise was the observational study written by Ekstrom et al found that there were no increased risks of acidosis/serious infection in patients with renal impairment according to the large numbers of patient...

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  • Mantoux testing may cause positive interferon gamma release assay results
    Michael Eisenhut

    The authors of a publication of a contact investigation described two children they labelled as having latent Mycobacterium (M.) tuberculosis infection: One 9-year old child had initially a negative interferon gamma release assay (IGRA) result when the initial Mantoux test was found to be positive with 8 mm. Three months later another IGRA was performed and found to be positive. The second patient was found to have a posi...

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  • Waste incineration, human health and the zero hypothesis
    Agostino Di Ciaula

    I read with great interest the article titled "Spatial analysis of health effects of large industrial incinerators in England, 1998-2008: a study using matched case-control areas" by Nicola F Reeve et al, published in BMJ Open 2013;3:e001847. The issue is of great relevance. The paper, however, contains some critical points that need to be underlined.

    1. The definition of "control" circles does not exclude the pr...

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  • RE:"National survey of US primary care physicians' perspectives about causes of obesity and solutions to improve care"
    Yvette L. Rooks

    RE:"National survey of US primary care physicians' perspectives about causes of obesity and solutions to improve care" Bleich SN, Bennett WL, Gudzune KA, et al. BMJ Open 2012;2:e001871. doi:10.1136/bmjopen-2012- 001871 http://bmjopen.bmj.com/content/2/6/e001871.abstract?sid=05bcca2b-326b-408b -9825-6569fe7970fd

    It was with great interest that I read Dr. Sara Bleich's study on primary care physicians' perspectives...

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  • Re:Second Reply: A Highly Biased and Flawed Study
    Megan A. Arroll

    Dear Dr Geraghty,

    This paper was based on a preliminary study and so was not 'perfect' by any means. BMJ Open states that in addition to more traditional studies "we also welcome more preliminary or only locally relevant research if it raises good questions and is cautiously interpreted". There are a number of limitations with this study and these have been discussed both in the paper and in our previous respons...

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  • Re:Didn't help me
    Megan A. Arroll

    Dear Dr Goudsmit,

    Thank you for your eletter.

    Are you referring to the following study?

    Paul, L., Wood, L., Behan, W.M.H., & Maclaren, W.M. (1999). Demonstration of delayed recovery from fatiguing exercise in chronic fatigue syndrome. European Journal of Neurology, 6, 63-69.

    I find no mention of ME in this paper, which uses the Fukuda et al. (1994) criteria for diagnosis of CFS....

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