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Systematic review to identify proxy indicators to quantify the impact of eHealth tools on maternal and neonatal health outcomes in low-income and middle-income countries including Delphi consensus
  1. Caroline Perrin,
  2. Lothaire Hounga,
  3. Antoine Geissbuhler
  1. Department of Radiology and Medical Informatics, Faculty of Medicine, University of Geneva, Geneva, Switzerland
  1. Correspondence to Caroline Perrin; caroline.perrin{at}hcuge.ch

Abstract

Objective To identify interventions that could serve as reliable proxy indicators to measure eHealth impact on maternal and neonatal outcomes.

Design Systematic review and Delphi study.

Methods We searched PubMed, Embase and Cochrane from January 1990 to May 2016 for studies and reviews that evaluated interventions aimed at improving maternal/neonatal health and reducing mortality. Interventions that are not low-income and middle-income context appropriate and that cannot currently be diagnosed, managed or impacted by eHealth (eg, via telemedicine distance diagnostic or e-learning) were excluded. We used the Cochrane risk of bias, Risk Of Bias In Non- randomised Studies - of Interventions and ROBIS tool to assess the risk of bias. A three-step modified Delphi method was added to identify additional proxy indicators and prioritise the results, involving a panel of 13 experts from different regions, representing obstetricians and neonatologists.

Results We included 44 studies and reviews, identifying 40 potential proxy indicators with a positive impact on maternal/neonatal outcomes. The Delphi experts completed and prioritised these, resulting in a list of 77 potential proxy indicators.

Conclusions The proxy indicators propose relevant outcome measures to evaluate if eHealth tools directly affect maternal/neonatal outcomes. Some proxy indicators require mapping to the local context, practices and available resources. The local mapping facilitates the utilisation of the proxy indicators in various contexts while allowing the systematic collection of data from different projects and programmes. Based on the mapping, the same proxy indicator can be used for different contexts, allowing it to measure what is locally and temporally relevant, making the proxy indicator sustainable.

PROSPERO registration number CRD42015027351.

  • information technology
  • telemedicine
  • maternal medicine
  • neonatology
  • health informatics

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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Footnotes

  • Contributors CP designed the work with input from AG. CP designed the protocol with input of AG and LH. CP did the initial screening of studies. CP and LH rated the studies; AG solved discrepancies in the ratings. CP extracted the data, which was thoroughly checked and verified by LH. CP drafted the article. AG and LH made a critical revision of the article. All authors gave their final approval of the version to be published.

  • Funding Department of Radiology and Medical Informatics, Faculty of Medicine, University of Geneva.

  • Competing interests None declared.

  • Patient consent Not required.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Data sharing statement No additional data sharing available.