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Use of a geographic information system to identify differences in automated external defibrillator installation in urban areas with similar incidence of public out-of-hospital cardiac arrest: a retrospective registry-based study
  1. David Fredman1,
  2. Jan Haas2,
  3. Yifang Ban2,
  4. Martin Jonsson1,
  5. Leif Svensson1,
  6. Therese Djarv3,
  7. Jacob Hollenberg1,
  8. Per Nordberg1,
  9. Mattias Ringh1,
  10. Andreas Claesson1
  1. 1Department of Medicine, Karolinska Institutet, Center for Resuscitation Science, Solna, Sweden
  2. 2Division of Geoinformatics, Kungliga Tekniska Hogskolan (KTH), Stockholm, Sweden
  3. 3Department of Medicine, Karolinska Institutet, Function of Emergency Medicine, Karolinska University Hospital, Stockholm, Sweden
  1. Correspondence to David Fredman; david.a.fredman{at}ki.se

Abstract

Objectives Early defibrillation in out-of-hospital cardiac arrest (OHCA) is of importance to improve survival. In many countries the number of automated external defibrillators (AEDs) is increasing, but the use is low. Guidelines suggest that AEDs should be installed in densely populated areas and in locations with many visitors. Attempts have been made to identify optimal AED locations based on the incidence of OHCA using geographical information systems (GIS), but often on small datasets and the studies are seldom reproduced. The aim of this paper is to investigate if the distribution of public AEDs follows the incident locations of public OHCAs in urban areas of Stockholm County, Sweden.

Method OHCA data were obtained from the Swedish Register for Cardiopulmonary Resuscitation and AED data were obtained from the Swedish AED Register. Urban areas in Stockholm County were objectively classified according to the pan-European digital mapping tool, Urban Atlas (UA). Furthermore, we reclassified and divided the UA land cover data into three classes (residential, non-residential and other areas). GIS software was used to spatially join and relate public AED and OHCA data and perform computations on relations and distance.

Results Between 1 January 2012 and 31 December 2014 a total of 804 OHCAs occurred in public locations in Stockholm County and by December 2013 there were 1828 AEDs available. The incidence of public OHCAs was similar in residential (47.3%) and non-residential areas (43.4%). Fewer AEDs were present in residential areas than in non-residential areas (29.4% vs 68.8%). In residential areas the median distance between OHCAs and AEDs was significantly greater than in non-residential areas (288 m vs 188 m, p<0.001).

Conclusion The majority of public OHCAs occurred in areas classified in UA as ‘residential areas‘ with limited AED accessibility. These areas need to be targeted for AED installation and international guidelines need to take geographical location into account when suggesting locations for AED installation.

  • Out-of-hospital cardiac arrest
  • OHCA
  • Automated External Defibrillator
  • AED
  • Urban Atlas
  • GIS.

This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/

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Strengths and limitations of this study

  • We have used rather simple GIS analyses available in most GIS software.

  • The UA dataset of European land use and cover is freely available and therefore it is possible to reproduce our analyses.

  • We do not identify high-risk areas for OHCAs or locations for AED installation but merely present the spatial relation of public AEDs and public OHCAs in Stockholm.

  • The Swedish AED registry (SAEDREG) only holds information voluntarily reported by AED owners and lacks information on any AEDs sold but not registered in SAEDREG.

  • Due to the data format for population density provided by Statistics Sweden, no analysis regarding demographics was performed in conjunction with the UA classifications.

Introduction

Out-of-hospital cardiac arrest (OHCA) is a major public health problem in Europe, affecting some 300 000 people each year1 with generally low survival rates of 5–10%.2 3 However, survival rates around 70% have been shown in cases where an automated external defibrillator (AED) is used by laypersons or trained non-medical responders within the first 3–5 min.4 5 During the last decade there has been an increase in the number of publicly available AEDs in many countries including Sweden,5–7 but the reported overall use of AEDs in OHCA is still relatively low ranging from 1.7% to 12.8%.5 8 9 Public AEDs are considered beneficial for OHCA in public locations,10 but AED installation in the homes of patients at risk for OHCA has not shown increased survival.11

Factors such as AED accessibility, bystander awareness and willingness to act and long distances from the location of OHCA to an AED may affect AED use.7 12–14 A distance of 100 metres between OHCA and AED is considered favourable for achieving defibrillation within the critical 3–5 min after collapse.15 16 To facilitate early defibrillation, recent guidelines from the European Resuscitation Council (ERC) suggest that AEDs should be placed in densely populated areas and in locations with many visitors such as train and bus stations, airports, sport facilities, casinos and shopping malls.1 Efforts have been made to identify optimal locations for public AEDs by analysing OHCA incidence and/or AED locations using geographical information systems (GIS).16–19 These studies are often carried out on relatively small datasets in a single city or limited regions and they use diverse GIS methods, which may limit their reproducibility and generalisability.

The aim of this paper was to investigate if the distribution of public AEDs follows the incident locations of public OHCA in urban areas of Stockholm County, Sweden.

Methods

Study area

Stockholm County contains the capital of Sweden and comprises 26 political municipalities. Covering 6526 km2 with 2 231 439 inhabitants (342/km2), Stockholm County is the most densely populated county of Sweden. However, including sparsely populated rural areas, over 70% of the population in Stockholm County are situated in areas classified as Urban core and Outer urban areas.20–22

In Stockholm County there is a two-tiered nurse-staffed ambulance system providing advanced life support in OHCA. In addition, a dual—or in some cases triple—dispatch of fire department and police alongside the ambulance is used to shorten delay from call to arrival and enable earlier defibrillation.23 24

Data collection

Data were collected from the following sources.

Swedish Register for Cardiopulmonary Resuscitation (SRCR)

SRCR is a national population-based register including OHCA data since 1990 and all OHCA cases where the ambulance crew has initiated cardiopulmonary resuscitation (CPR) are reported to SRCR.25 OHCA cases are collected prospectively by the ambulance crew and case characteristics, bystander performance and interventions on-scene by the emergency medical service (EMS) is reported in accordance with the 2004 Utstein-style recommendations.25 26 However, SRCR includes some more specific locations of OHCA such as train station, church and airport.25 27 Since 2007, OHCA cases are reported in close connection to the corresponding emergency call through a web-based system and, from 2011, SRCR is estimated to include 100% of the OHCA cases in Sweden.25

Swedish AED Register (SAEDREG)

SAEDREG is a non-compulsory register of public AEDs in Sweden and contains information entered by AED owners on AED location (ie, address and coordinates) and accessibility (ie, access hours and owners’ contact information). SAEDREG was established in 2009 and is managed by the Swedish CPR council. To ensure a high level of validity, an automated reminder is emailed every 6 months after registration and AED owners are asked to verify all entered data. Only owner-verified AED information is displayed on the SAEDREG web page. By December 2013, SAEDREG held information on 7078 AEDs.25 According to the Swedish Resuscitation Council, this accounts for 36% of the AEDs sold in Sweden based on figures from the AED companies in Sweden.25

Urban Atlas digital mapping tool

Urban Atlas (UA) is part of the European Commission’s Global Monitoring of Environment and Security (GMES) land monitoring service. UA is pan-European and based on satellite images with a 2.5 metre resolution and provides digital high-resolution land cover maps of 299 larger urban zones in the European Union including all capital cities of member states.28 UA data are supported by reference data such as topographic maps and contain 19 land use/land cover classes.28 UA data are freely available in the form of shape files from the European Environment Agency website.29 UA is primarily intended as inter-comparable and reliable urban planning data and is well-known and used for GIS analyses of urban areas in Europe.30–32

Selection of public OHCA cases

From the SRCR, OHCA cases in which the EMS crew reported the location for collapse as being in public locations (ie, outside the home) were selected for the analysis. Cases reported as witnessed by the EMS crews were excluded.

Selection of publicly available AEDs

From SAEDREG, all publicly available AEDs in Stockholm County at 31 December 2013 were selected, regardless of location and opening hours of the AED venues.

Obtaining geographical information

The geographical locations of AEDs in Stockholm County were obtained from SAEDREG in the form of coordinate pairs in the RT90 coordinate system.33 The SRCR data did not contain addresses or coordinates of incidence locations of OHCA. The national dispatch organisation in Sweden stores the coordinates of all emergency calls in the incident logs. By matching the incident codes of the selected OHCA cases from SRCR with the incident logs from the dispatch centre in Stockholm County, the geographical coordinates were obtained in the form of coordinate pairs in the WGS84 coordinate system.34

To facilitate further GIS analysis and to preserve the distance relations, the two datasets were converted to the SWEREF99 coordinate system.35

Categorisation of urban areas

For analysis of the geographical distribution of public OHCAs and public AEDs in urban areas of Stockholm County we used the classification: land with human activity or non-agricultural, taken from the UA decision matrix. These urban areas were reclassified as either: (1) residential areas; (2) non-residential areas; or (3) other areas, based on their dominant land use and land cover. The definitions and descriptions of the UA subcategories are found in section 4.6. of the mapping guide for UA.28

UA and it´s classifications do not account for population density, inhabitants or visitors over time in these areas. It is merely a classification of the area's predominant use.28

The residential area class was aggregated from six UA land cover subcategories defined as areas with dominant residential or inner-city areas with central business districts and residential use. Non-residential areas comprise artificial surfaces where industrial, commercial or leisure and recreational use are predominant.

Areas defined in UA as road and rail networks and as areas with a strong human influence but not containing specific information determining if the area is residential or non-residential (ie, construction sites, dump sites and land without current use) were removed from the UA layer, and public OHCA and AEDs in these locations were coded as the nearest neighbouring area. For example, an OHCA occurring on a road passing through a residential area was coded as having occurred in the surrounding area, and an OHCA occurring at a construction site within a non-residential area was consideredto occur  in the surrounding or neighbouring area . The class 'other areas' was created from land with little or no human influence, in UA defined as agricultural, semi-natural areas, wetlands and forests.28 Areas of Stockholm County defined in UA as water were excluded from analysis of OHCA and AED locations. Figure 1 gives a closer description of the urban subcategories including map cut-outs for easier interpretation and shows the reclassification of residential and non-residential areas.

Figure 1

Description of the Urban Atlas (UA) subcategories creating the residential and non-residential areas of Stockholm, Sweden including map cut-outs for visualisation. The text includes the original UA subcategory numbering as well as UA land use and land cover descriptions. R, residential area (R1–R6);NR, non-residential area (NR1-NR4); UA, Urban Atlas.

In the new residential and non-residential area categories, the subcategories from UA were kept but renamed for easier referral. The residential area subcategories were named R (for residential) and numbered R1 to R6 (figure 1). The numbering indicates a decreasing continuity of building density and soil sealing from R1 (the most dense urban area) to R5 (defined as a discontinuous urban area of very low density) and R6 (isolated structures) according to the UA decision matrix.28 The non-residential area subcategories were named NR (for non-) and numbered NR1 to NR4 (figure 1).

GIS computation of public OHCA and AED relations

To identify the locations of public OHCA incidence and AEDs, the respective coordinates were joined with the UA layer using the spatial join tool in the GIS software QGIS 2.10.36 For comparison of Euclidean distance (ie, straight line distance between OHCA and the nearest AED), the function 'nearest neighbour' in QGIS 2.10 was used.

Statistics

Descriptive statistics were calculated in IBM SPSS 22.0 for Mac (IBM, Armonk, NewYork, USA). The Mann–Whitney U-test was used to test significance for continuous variables. p Values of correlation were calculated with Spearman’s rank correlation coefficient and p values <0.05 were considered statistically significant.

Results

Between 1 January 2012 and 31 December 2014 a total of 804 OHCAs occurred in public locations in Stockholm County and 1828 publicly available AEDs in the region were registered in SAEDREG by 31 December 2013.

The reclassified land use/land cover data comprises 643 km2 of residential areas, 311 km2 of non-residential areas and 5220 km2 of other areas (table 1). Further on in this section the relationship between public OHCAs and AEDs is presented for the new land use classes residential and non-residential areas. The results for other areas are presented solely in table 1.

Table 1

Locations of public out-of-hospital cardiac arrests (OHCAs) and automated external defibrillators (AEDs) in urban areas of Stockholm, Sweden and characteristics for distance from OHCA to AED, ambulance response time and 30-day survival per urban area

There were only small differences in the incidence of public OHCAs between the three urban areas in relation to daily or yearly temporal variation.

Public OHCA incident locations

In the new land use class defined as residential areas, 380 (47.3%) of the public OHCAs occurred compared with 349 (43.4%) in non-residential areas. The largest proportion of public OHCAs in the subcategories residential and non-residential areas was in R3 where 104 (12.9%) occurred and in NR1 where 228 (28.4%) occurred (table 1).

Public AED locations

Of the publicly available AEDs, 537 (29.4%) were located in residential areas and 1258 (68.8%) were located in non-residential areas. The largest proportion of all public AEDs in the subcategories of residential and non-residential areas was in R1 where 14.6% were located and in NR1 where 59% were located (table 1).

Public OHCA incident locations and public AED locations

In residential areas the highest proportion of public OHCAs (27%, 104/380) occurred in R3 where the AED proportion was 11% (59/537). The highest proportion of AEDs in residential areas (50%, 267/537) was found in R1 where 21% (80/380) of the public OHCAs occurred. In non-residential areas the highest proportion of public OHCAs (65%, 228/349) was in NR1 where the highest proportion of AEDs (86%, 1079/1258) was also found (table 1).

Median distance from OHCA to AED

The median distance from public OHCA to the nearest AED was significantly shorter in non-residential areas than in residential areas (188 m vs 288 m, p<0.001). The IQR was 60.0–475.1 m for residential areas and 120.8–655.6 m for non-residential areas.

The two subcategories with the largest proportions of public OHCA (R3 in residential areas and NR1 in non-residential areas) had a median distance of 355 m and 141.6 m, respectively, from the OHCA to the nearest AED. The shortest median distance from a public OHCA to the nearest AED and the only median distance below 100 m was found in subcategory R1 (table 1).

Discussion

The main finding of this study is that, even though the incidence locations of public OHCA in Stockholm County were evenly distributed between areas defined by UA28 as residential and non-residential areas, more than two-thirds of the available AEDs were located in non-residential areas.

Figure 2 depicts the locations of public AEDs and public OHCA incidences in the central and closest suburban areas of Stockholm city and figure 3 displays a close-up of an area where the mismatch between OHCA incidence locations and AED installations in residential and non-residential areas is clearly visible.

Figure 2

A map of the central and closest suburban areas of Stockholm, Sweden visualising the representation of residential and non-residential areas according to our reclassification of the Urban Atlas (UA) land cover classes and the distribution of public OHCA locations and AED locations. AED, automated external defibrillator; OHCA, out-of-hospital cardiac arrest.

Figure 3

Close-up of an area just south-west of the central parts of Stockholm, Sweden. This visualises the mismatch in public OHCA incidence and AED locations between residential and non-residential areas. AED, automated external defibrillator; OHCA, out-of-hospital cardiac arrest.

OHCA incidence location

According to the Utstein Resuscitation Registry templates, the specific location of an OHCA should be reported to aid communities to optimise resources. The Utstein template for reporting OHCA incident locations suggests the following reporting options: home/residence; industrial/workplace; sports/recreation event; institution; other and unspecified/unknown/not recorded.37

Data on public OHCA incidence in the present study were acquired from the SRCR, an Utstein style cardiac arrest registry with a high level of inclusion and validity38 that uses a modified Utstein template for reporting the incidence location of OHCAs.25 In Sweden, ‘street and square’ is the most common reported location for OHCAs in public locations over the last 8 years, comprising 7.6% of 17 756 reported OHCAs.25 Nonetheless, residential locations are still the most common location for OHCAs in Sweden25 and internationally.9 39

An OHCA reported as occurring in a street location could have dramatically different likelihood for AED use, depending on whether the street location is on the parking lot of a large shopping mall or on the kerb outside a suburban housing area—that is, in a non-residential or residential area according to the UA classification. The same may apply for bystander CPR rates in different locations based on numbers of visitors and accessibility, but this is not analysed in the present study.

A study from Japan reported that 9.5% of bystander-witnessed OHCAs occurred in public locations. A high rate of AED use was reported from railway stations (41.2%) and sport facilities (56.5%), although with low actual numbers of cases (n=17 and n=23, respectively). However, 562 (68%) of the public OHCAs in the study reportedly occurred in locations defined as ‘other’ according to the Utstein template, and here the AED use was as low as 3.6%.9 It is reasonable to believe—but not further elaborated on—that these ‘other’ locations are very diversified.

We believe the data reporting options suggested by the Utstein template may somewhat limit the understanding of the low AED usage.

In the present study we have analysed all OHCAs in public locations, regardless of the location reported in SRCR. This method of including all public OHCAs regardless of locations allowed us to include and analyse OHCA cases in locations reported as ‘unknown’ or ‘other’, in contrast to the Japanese study, and this revealed an equal incidence of public OHCAs in residential or non-residential areas. This, in our opinion, more objective approach to analysing incidence locations of public OHCAs and AEDs based on area rather than the traditional more subjective use of locations reported by ambulance crews, could add valuable insights to this field of research. Figure 3 visualises an area of Stockholm where the mismatch between public OHCA incidence locations and AED installation sites is clearly visible.

It is, however, important to clarify that UA and the subcategory classifications used in this work do not reflect population density, inhabitants or number of visitors.

AED location

In the present study two-thirds of the AEDs were located in non-residential areas. A Canadian study reported similar findings when categorising public OHCA incident locations and AED installation sites as either in or outside the downtown area. The study reported that the downtown area had a greater AED coverage of public OHCAs than outside the downtown area (49% vs 17%), but at the same time 80% of the public OHCAs occurred outside the downtown area.17 This indicates a tendency for AED installations in commercial areas of the urban environment.

Current European Resuscitation Council guidelines suggest that AEDs should be placed in locations with many visitors and specifically point out public locations such as train and bus stations, airports, sport facilities, casinos and shopping malls.1 However, the guidelines also suggest that AEDs should be placed in densely populated areas but do not specify such locations or the appropriate level of density.1 In the present study we noted a higher public OHCA incidence in residential areas which, according to UA, consist of low and medium density housing areas, than in areas of a more dense character28 (table 1 and figure 1). This raises the question of how densely populated an area should be in order to be considered a target for AED installation.

With guidelines specifically pointing out locations for AED installation mainly present in areas in UA defined as non-residential areas, an unfavourable mismatch between AED locations and public OHCA incidence locations may be the result, as the present study suggests.

Previous work from the USA described a poor association between location of OHCAs and AED placements and stated that no AEDs were located in the most frequent locations for OHCAs.40 That study included OHCAs in patients' homes, which we believe may obscure the analysis of associations between OHCA and AED locations. Previous work concludes that public AED use is most effective in public settings10 41 42 and not in peoples' homes.11 Systems that use mobile telephones to alert volunteer laypersons to reach OHCA victims in their home environment have been introduced.43–46 This may somewhat eliminate the effect of mismatch in AED installations shown in the present study.

Some caution should be observed when using UA for evaluating health outcomes since it was primarily developed as a tool for pan-European urban planning purposes. Our findings of relationships between public OHCA and AED locations need to be verified in or between other cities, regions or countries. With the UA datasets freely downloadable for most major cities/urban zones of the European Union, a reproduction of our study is possible if AED and OHCA registries with geocoded datasets are available.

Based on the findings from the present study, we aim to identify possible locations for AED installations more evenly distributed between residential and non-residential areas of Stockholm County.

Distance from OHCA to AED

We noticed a significantly lower median distance between public OHCAs and AEDs in non-residential areas compared with residential areas. A possible explanation is that area size and AED enumeration is the key to a favourable distance or coverage (table 1). A distance of 100 metres to the nearest AED is assumed an 'upper limit’ for defibrillation within the early critical 3–5 min.15 16 18 A median distance of less than 100 metres only appeared in the smallest (6.6 km2) residential area subcategory, R1. According to UA reference publications, this subcategory includes downtown areas and city centres.28 In this area the highest AED/100 km2 value is identified, due to its small size but high rate of AEDs (table 1).

The previously mentioned Canadian study showed a 60% lower median distance between public OHCAs and AEDs in downtown areas. The authors reflect on the shorter median distance being a result of higher numbers of AEDs located in a smaller area.17 This raises the question whether the AED/100 km2 ratio may be as valid as the suggested 100 metre distance, widely adopted , but not verified by randomised trials.

Conclusion

Our results show that the majority of public OHCAs in Stockholm County occur in areas classified in UA as residential areas, where AED accessibility is limited. Our findings indicate that residential areas need to be considered priority targets for AED installation and that looking at area rather than location, using geodata tools such as UA and GIS, can contribute to identifying these areas. We also believe that international guidelines need to take geographical location into account when suggesting locations for AED installations.

Acknowledgments

We wish to thank Mona Bergström-Ling at the national dispatch organisation SOS Alarm AB, Stockholm, for invaluable help in the retrieving of GPS coordinates for the OHCA cases. We wish to give a virtual 'high-five' to Marvin McCutchan at KTH for the great work with the visualisation of the figures.

References

  1. 1.
  2. 2.
  3. 3.
  4. 4.
  5. 5.
  6. 6.
  7. 7.
  8. 8.
  9. 9.
  10. 10.
  11. 11.
  12. 12.
  13. 13.
  14. 14.
  15. 15.
  16. 16.
  17. 17.
  18. 18.
  19. 19.
  20. 20.
  21. 21.
  22. 22.
  23. 23.
  24. 24.
  25. 25.
  26. 26.
  27. 27.
  28. 28.
  29. 29.
  30. 30.
  31. 31.
  32. 32.
  33. 33.
  34. 34.
  35. 35.
  36. 36.
  37. 37.
  38. 38.
  39. 39.
  40. 40.
  41. 41.
  42. 42.
  43. 43.
  44. 44.
  45. 45.
  46. 46.
View Abstract

Footnotes

  • Contributors Study concept and design: DF, MJ, JH, YB, AC, LS.

    Acquisition of data: DF, MJ, JH.

    Analysis and interpretation of data: DF, MJ, JH.

    Drafting of the manuscript: DF, MJ, AC, LS.

    Critical revision of the manuscript for important intellectual content: DF, MJ, LS, AC, YB, TD, JH, MR, PN.

    Statistical analysis: DF, MJ, JH.

    Obtained funding: LS.

    Study supervision: AC, LS, YB.

  • Funding This work was supported by a centre support grant from the Laerdal Foundation and by unrestricted grants from Hjärt-lungfonden (the Swedish Heart and Lung Foundation) and Stockholm County Council. These funders had no role in study design, data collection and analysis, decision to publish or preparation of the manuscript.

  • Competing interests None declared.

  • Ethics approval The regional ethics committee in Stockholm County approved the study, (2014/1134-31/2).

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Data sharing statement Availability of data and material: The OHCA and AED data supporting the findings of this study are available upon reasonable request, but restrictions apply to the availability and sharing of these data, which were used by the authors under license for the current study. Data are available from the following sources: Swedish AED data can be obtained by special permission from the owner of the SAEDREG, the Swedish Resuscitation Council (info@hlr.nu). Data on OHCA incident locations from SRCR can be obtained by special permission from Registercentrum Västra Götaland, Sweden. Urban Atlas shapefiles are freely downloadable from the European Environment Agency .

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